Being the most delicate organ of the body, the brain is protected against potentially toxic
substances by the blood-brain barrier (BBB), which restricts the entry of most …

Nanoparticle-based radiosensitization of cancerous cells is evolving as a favorable modality
for enhancing radiotherapeutic ratio, and as an effective tool for increasing the outcome of …

Postsurgical treatment of glioblastoma multiforme (GBM) by systemic chemotherapy and
radiotherapy is often inefficient. Tumor cells infiltrating deeply into the brain parenchyma are …

Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …

Brain cancer is a devastating disease affecting many people worldwide. Effective treatment
with chemotherapeutics is limited due to the presence of the blood-brain barrier (BBB) that …

The blood-brain barrier (BBB) inhibits the entry of the majority of chemotherapeutic agents
into the brain. Previous studies have illustrated the feasibility of drug delivery across the BBB …

Brain delivery of drugs by nanoparticles is a promising strategy that could open up new
possibilities for the chemotherapy of brain tumors. As demonstrated in previous studies, the …

The blood–brain-barrier (BBB) prevents the transport of most anticancer agents to the
central nervous system and restricts delivery to infiltrating brain tumors. The heterogeneous …

Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Surface-enhanced Raman scattering (SERS) technique is becoming highly popular for
multiplex biosensing due to the 'fingerprint'Raman spectra from every molecule. As a proof …