FDA-approved drugs with potent in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2
(1) Background: Drug repositioning is an unconventional drug discovery approach to
explore new therapeutic benefits of existing drugs. Currently, it emerges as a rapid avenue …
explore new therapeutic benefits of existing drugs. Currently, it emerges as a rapid avenue …
Naringenin as a possible candidate against SARS-CoV-2 infection and in the pathogenesis of COVID-19
PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Naringenin, widely distributed in fruits and vegetables, is endowed with antiviral and other
health beneficial activities, such as immune-stimulating and anti-inflammatory actions that …
health beneficial activities, such as immune-stimulating and anti-inflammatory actions that …
Novel Drug Design for Treatment of COVID‐19: A Systematic Review of Preclinical Studies
Background. Since the beginning of the novel coronavirus (SARS‐CoV‐2) disease
outbreak, there has been an increasing interest in discovering potential therapeutic agents …
outbreak, there has been an increasing interest in discovering potential therapeutic agents …
Identification of alkaloids from Justicia adhatoda as potent SARS CoV-2 main protease inhibitors: An in silico perspective
R Ghosh, A Chakraborty, A Biswas… - Journal of molecular …, 2021 - Elsevier
The COVID-19 pandemic, caused by SARS CoV-2, is responsible for millions of death
worldwide. No approved/proper therapeutics is currently available which can effectively …
worldwide. No approved/proper therapeutics is currently available which can effectively …
Comprehensive virtual screening of 4.8 k flavonoids reveals novel insights into allosteric inhibition of SARS-CoV-2 MPRO
G Jiménez-Avalos, AP Vargas-Ruiz… - Scientific reports, 2021 - nature.com
SARS-CoV-2 main protease is a common target for inhibition assays due to its high
conservation among coronaviruses. Since flavonoids show antiviral activity, several in silico …
conservation among coronaviruses. Since flavonoids show antiviral activity, several in silico …
In silico study of natural compounds from sesame against COVID-19 by targeting M pro, PL pro and RdRp
Natural products and traditional medicine products with known safety profiles are a
promising source for the discovery of new drug leads. Natural products as sesame were …
promising source for the discovery of new drug leads. Natural products as sesame were …
Chemical constituents from Carica papaya Linn. leaves as potential cytotoxic, EGFR wt and aromatase (CYP19A) inhibitors; a study supported by molecular docking
The phytochemical investigation of the hydromethanolic extract of Carica papaya Linn.
leaves (Caricaceae) resulted in the isolation and characterization of ten compounds …
leaves (Caricaceae) resulted in the isolation and characterization of ten compounds …
Identification of Potential SARS-CoV-2 Main Protease and Spike Protein Inhibitors from the Genus Aloe: An In Silico Study for Drug Development
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) disease is a global rapidly
spreading virus showing very high rates of complications and mortality. Till now, there is no …
spreading virus showing very high rates of complications and mortality. Till now, there is no …
Identification of potential bioactive natural compounds from Indonesian medicinal plants against 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2: molecular …
WE Prasetyo, H Purnomo, M Sadrini… - Journal of …, 2023 - Taylor & Francis
An outbreak of SARS-CoV-2 (COVID-19) has caused a global health emergency, resulting
in hundreds of millions of infections and millions of deaths globally since December 2019 …
in hundreds of millions of infections and millions of deaths globally since December 2019 …
Theoretical investigation of favipiravir antiviral drug based on fullerene and boron nitride nanocages
KA Soliman, SA Aal - Diamond and related materials, 2021 - Elsevier
Smart implementation of novel advanced nanocarriers such as functionalized C 24 and B 12
N 12 nanocages is used supplement for antiviral activity 5-Fluoro-2-hydroxypyrazine-3 …
N 12 nanocages is used supplement for antiviral activity 5-Fluoro-2-hydroxypyrazine-3 …