Hydrogels for protein delivery

T Vermonden, R Censi, WE Hennink - Chemical reviews, 2012 - ACS Publications
Importantly, with the advent of hybridoma and recombinant DNA technologies, the limitations
associated with the extraction and purification of pharmaceutical proteins from animal …

Functional aliphatic polyesters for biomedical and pharmaceutical applications

H Seyednejad, AH Ghassemi, CF van Nostrum… - Journal of Controlled …, 2011 - Elsevier
Functional aliphatic polyesters are biodegradable polymers with many possibilities to tune
physico-chemical characteristics such as hydrophilicity and degradation rate as compared to …

Issues in long-term protein delivery using biodegradable microparticles

M Ye, S Kim, K Park - Journal of Controlled Release, 2010 - Elsevier
Recently, a variety of bioactive protein drugs have been available in large quantities as a
result of advances in biotechnology. Such availability has prompted development of long …

Physicochemical properties and applications of poly (lactic-co-glycolic acid) for use in bone regeneration

RPF Lanao, AM Jonker, JGC Wolke… - … Engineering Part B …, 2013 - liebertpub.com
Poly (lactic-co-glycolic acid)(PLGA) is the most often used synthetic polymer within the field
of bone regeneration owing to its biocompatibility and biodegradability. As a consequence …

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in …

B Slütter, S Bal, C Keijzer, R Mallants, N Hagenaars… - Vaccine, 2010 - Elsevier
Nasal vaccination is a promising, needle-free alternative to classical vaccination.
Nanoparticulate delivery systems have been reported to overcome the poor immunogenicity …

Use of poly lactic-co-glycolic acid nano and micro particles in the delivery of drugs modulating different phases of inflammation

C Puricelli, CL Gigliotti, I Stoppa, S Sacchetti… - Pharmaceutics, 2023 - mdpi.com
Chronic inflammation contributes to the pathogenesis of many diseases, including
apparently unrelated conditions such as metabolic disorders, cardiovascular diseases …

Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer

S Rahimian, MF Fransen, JW Kleinovink, M Amidi… - Biomaterials, 2015 - Elsevier
This study investigated the feasibility of the use of polymeric microparticles for sustained and
local delivery of immunomodulatory antibodies in immunotherapy of cancer. Local delivery …

A review of immobilization techniques to improve the stability and bioactivity of lysozyme

PT Anastas, A Rodriguez, TM de Winter… - … Chemistry Letters and …, 2021 - Taylor & Francis
Lysozyme is a naturally occurring enzyme with antimicrobial activity that has gained
significant attention for its potential use in a range of industrial applications. Due to its low …

The effect of lauryl capping group on protein release and degradation of poly (d, l-lactic-co-glycolic acid) particles

N Samadi, A Abbadessa, A Di Stefano… - Journal of Controlled …, 2013 - Elsevier
The aim of this study was to investigate the effect of a specific and frequently used end group
(lauryl alcohol) on the protein release and degradation kinetics of poly (DL-lactic-co-glycolic …

Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advances

J Zhang, J Fan, M Skwarczynski… - International Journal …, 2022 - Taylor & Francis
Persistent infection with high-risk human papillomaviruses (HPVs), such as HPV-16 and
HPV-18, can induce cervical cancer in humans. The disease carries high morbidity and …