Abstract N6-methyladenosine (m 6 A) is one of the most common RNA modifications in
eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m 6 A …

Osteoporosis is a prevalent bone disease of the aging population, which is characterized by
a decrease in bone mass because of the imbalance of bone metabolism. Although the …

Epigenetic regulation involves a range of sophisticated processes which contribute to
heritable alterations in gene expression without altering DNA sequence. Regulatory events …

Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …

Abstract N 6-methyladenosine (m 6 A), a novel epitranscriptomic RNA modification, plays
crucial roles in a variety of biological processes and diseases. Recently, there are growing …

With the markedly increased diagnosis and incidence of cancer in the population, tumor
bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is …

Fracture combined with traumatic brain injury (TBI) is one of the most common and serious
types of compound trauma in the clinic and is characterized by dysfunction of cellular …

Methylation is the most common posttranscriptional modification in cellular RNAs, which has
been reported to modulate the alteration of RNA structure for initiating relevant functions …

Background Sepsis-associated acute kidney injury (SA-AKI) is one of the most frequent and
serious complications of sepsis. However, the transcriptional regulatory network of the …

Objectives Bone marrow mesenchymal stem cells (BMSCs) hold a high osteogenic
differentiation potential, but the mechanisms that control the osteogenic ability of BMSCs …