Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …

On-line analysis of exhaled breath offers insight into a person's metabolism without the need
for sample preparation or sample collection. Due to its noninvasive nature and the possibility …

The heme protein myeloperoxidase (MPO) is a major constituent of neutrophils. As a key
mediator of the innate immune system, neutrophils are rapidly recruited to inflammatory …

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease
characterized by chronic airway obstruction and emphysema. Accumulating studies have …

First-and second-hand exposure to smoke or air pollutants is the primary cause of chronic
obstructive pulmonary disease (COPD) pathogenesis, where genetic and age-related …

Summary Background Alpha-1 Antitrypsin (AAT) deficiency (AATD), the most common
genetic cause of emphysema presents with unexplained phenotypic heterogeneity in …

In the context of respiratory disease, chronic obstructive pulmonary disease (COPD) is the
leading cause of mortality worldwide. Despite much development in the area of drug …

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a major global health problem.
Among other conditions, it has been associated with chronic airway and lung parenchyma …

Alpha-1 antitrypsin deficiency (AATD) is caused by a single mutation in the SERPINA1 gene,
which culminates in the accumulation of misfolded alpha-1 antitrypsin (ZAAT) within the …

Introduction The objective of this analysis was the evaluation of a new national circuit used
for diagnosing alpha1 antitrypsin deficiency (AATD) based on multiplex technology using …