Myotonic dystrophy type 1 (DM1) is the most common muscular dystrophy that affects
multiple systems including the muscle and heart. The mutant CTG expansion at the 3′-UTR …

Abstract Myotonic dystrophy type 1 (DM1) is a multisystemic and heterogeneous disorder
caused by the expansion of CTG repeats in the 3'UTR of the myotonic dystrophy protein …

Abstract Myotonic dystrophy type 1 (DM1), the most common form of adult-onset muscular
dystrophy, is caused by a CTG expansion resulting in significant transcriptomic …

Sepsis, defined as a dysregulated host immune response to infection, is a common and
dangerous clinical syndrome. The excessive host inflammatory response can induce …

Brain dysfunction in myotonic dystrophy type 1 (DM1), the prototype of toxic RNA disorders,
has been mainly attributed to neuronal RNA misprocessing, while little attention has been …

Myotonic dystrophy (DM) is a dominantly inherited multisystemic disorder affecting various
organs, such as skeletal muscle, heart, the nervous system, and the eye. Myotonic dystrophy …

Neuro-muscular disorders include a variety of diseases induced by genetic mutations
resulting in muscle weakness and waste, swallowing and breathing difficulties. However …

Muscular dystrophies vary in presentation and severity, but are associated with profound
disability in many people. Although characterised by muscle weakness and wasting, there is …

Omics studies are crucial to improve our understanding of myotonic dystrophy type 1 (DM1),
the most common muscular dystrophy in adults. Employing tissue samples and cell lines …

Olfactory loss accompanies at least 139 neurological, somatic, and congenital/hereditary
conditions. This observation leads to the question of whether these associations are …