Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …

Protein misfolding and aggregation, a key contributor to the progression of numerous
neurodegenerative diseases, results in functional deficiencies and the creation of harmful …

Hydroxyl radical protein footprinting (HRPF) coupled to mass spectrometry has been
successfully used to investigate a plethora of protein-related questions. The method, which …

Antibodies have been used to prevent or treat viral infections since the nineteenth century,
but the full potential to use passive immunization for infectious diseases has yet to be …

Conspectus Assessment of protein structure and interaction is crucial for understanding
protein structure/function relationships. Compared to high-resolution structural tools …

Fast photochemical oxidation of proteins (FPOP) is a MS-based method that has proved
useful in studies of protein structures, interactions, conformations, and protein folding. The …

Using mass spectrometry (MS) to obtain information about a higher order structure of protein
requires that a protein's structural properties are encoded into the mass of that protein …

Measles virus (MeV), a highly contagious member of the Paramyxoviridae family, causes
measles in humans. The Paramyxoviridae family of negative single-stranded enveloped …

Protein footprinting coupled with mass spectrometry has become a widely used tool for the
study of protein–protein and protein–ligand interactions and protein conformational change …

Langya virus (LayV) is a paramyxovirus in the Henipavirus genus, closely related to the
deadly Nipah (NiV) and Hendra (HeV) viruses, that was identified in August 2022 through …