[HTML][HTML] Molecular mechanisms of ROS-modulated cancer chemoresistance and therapeutic strategies

X Zhou, B An, Y Lin, Y Ni, X Zhao, X Liang - Biomedicine & …, 2023 - Elsevier
Drug resistance is the main obstacle to achieving a cure in many cancer patients. Reactive
oxygen species (ROS) are master regulators of cancer development that act through …

Current Status and Molecular Mechanisms of Resistance to Immunotherapy in Oral Malignant Melanoma

SZ Usta, T Uchihashi, S Kodama, K Kurioka… - International Journal of …, 2023 - mdpi.com
Immune checkpoint inhibitors (ICIs), including anti-cytotoxic T-lymphocyte-associated
protein 4 (CTLA-4) and anti-programmed death-1 (PD-1) antibodies, have initiated a new …

Comprehensive Analysis of Clinically Relevant Copy Number Alterations (CNAs) Using a 523-Gene Next-Generation Sequencing Panel and NxClinical Software in …

V Gupta, V Vashisht, A Vashisht, AK Mondal, A Alptekin… - Genes, 2024 - mdpi.com
Copy number alterations (CNAs) are significant in tumor initiation and progression.
Identifying these aberrations is crucial for targeted therapies and personalized cancer …

[HTML][HTML] Pathologic nodal metastasis assessment using tumour‐derived molecular features in patients with lung adenocarcinoma

S Wang, Z Zhou, S Wang, R Guo, Z Ma… - Clinical and …, 2024 - ncbi.nlm.nih.gov
Dear Editor, Through whole-exome sequencing (WES), we identified genomic features that
correlated with pathologic lymph node metastasis (pN) and poor patient prognosis in …

Molecular, Genetic Susceptibility and Immunotherapy of Melanoma

PV Shenoy, R Nag, KK Kolathur, Y Malik, SM Varanasi… - 2023 - preprints.org
Skin cancer is a prevalent and heterogenous disease with several subtypes, such as
melanoma, basal cell carcinoma, and squamous cell carcinoma. Among them, melanoma is …