Background: Cyclin-dependent kinase inhibitor 1C (CDKN1C) is a key negative regulator of
cell growth encoded by a paternally imprinted/maternally expressed gene in humans. Loss …

Xanthohumol (XN) is a natural anticancer compound that inhibits the proliferation of
oestrogen receptor-α (ERα)-positive breast cancer cells. However, the precise mechanism of …

The placenta, which is a regulator organ for many metabolic activities between mother and
fetus, is critical in influencing the outcome of pregnancy. Therefore, fetal growth is directly …

Fetal adrenal developmental status is the major determinant of fetal tissue maturation and
offspring growth. We have previously proposed that prenatal ethanol exposure (PEE) …

Introduction Fetal growth restriction (FGR) carries an increased risk of perinatal mortality and
morbidity. A major cause of FGR is placental insufficiency. After in utero chemotherapy …

Aims Placental physiology and morphology is critically regulated by DNA methylation. As
such, placental global DNA methylation and transcript abundance of placental DNA …

To investigate the effects of di-n-hexyl phthalate (DHP) and dicyclohexyl phthalate (DCHP)
on the development of fetus and placenta in utero, pregnant rats were exposed to DHP or …

Background/aims Preeclampsia is a pregnancy-specific disease with the increased risk of
maternal morbidity and mortality. It is characterised by placental vascular dysfunction …

Fetal growth restriction (FGR) is one of the major complications of pregnancy, which can
lead to serious short-term and long-term diseases. High-mobility group box 3 (HMGB3) has …

The syncytiotrophoblast, derived from cytotrophoblast fusion, is responsible for maternal-
fetal exchanges, secretion of pregnancy-related hormones, and fetal defense against …