Prevention and periodontal treatment in Down syndrome patients: a systematic review
R Ferreira, RC Michel, SLA Greghi, MLR Resende… - PloS one, 2016 - journals.plos.org
The aim of this systematic literature review was to evaluate which type of periodontal
preventive and therapeutic approaches presents superior outcomes in patients with Down …
preventive and therapeutic approaches presents superior outcomes in patients with Down …
Congenital heart disease: an immunological perspective
Congenital heart disease (CHD) poses a significant global health and economic burden—
despite advances in treating CHD reducing the mortality risk, globally CHD accounts for …
despite advances in treating CHD reducing the mortality risk, globally CHD accounts for …
Down syndrome developmental brain transcriptome reveals defective oligodendrocyte differentiation and myelination
Trisomy 21, or Down syndrome (DS), is the most common genetic cause of developmental
delay and intellectual disability. To gain insight into the underlying molecular and cellular …
delay and intellectual disability. To gain insight into the underlying molecular and cellular …
Immune dysregulation and the increased risk of complications and mortality following respiratory tract infections in adults with down syndrome
The risk of severe outcomes following respiratory tract infections is significantly increased in
individuals over 60 years, especially in those with chronic medical conditions, ie …
individuals over 60 years, especially in those with chronic medical conditions, ie …
Specific susceptibility to COVID-19 in adults with Down syndrome
The current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for
individuals with chronic medical conditions, in particular those with Down Syndrome (DS) …
individuals with chronic medical conditions, in particular those with Down Syndrome (DS) …
Vulnerability to disease as a predictor of faster life history strategies
Here we review research suggesting that vulnerability to disease plays a significant role in
modulating life history strategies. In particular, we highlight the role of immunocompetence …
modulating life history strategies. In particular, we highlight the role of immunocompetence …
Increased levels of inflammatory plasma markers and obesity risk in a mouse model of Down syndrome
Down syndrome (DS) is caused by the trisomy of human chromosome 21 and is the most
common genetic cause of intellectual disability. In addition to the intellectual deficiencies …
common genetic cause of intellectual disability. In addition to the intellectual deficiencies …
Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice
N Rueda, V Vidal, S García-Cerro, JO Narcís… - Brain, Behavior, and …, 2018 - Elsevier
Down syndrome (DS) is characterized by structural and functional anomalies that are
present prenatally and that lead to intellectual disabilities. Later in life, the cognitive abilities …
present prenatally and that lead to intellectual disabilities. Later in life, the cognitive abilities …
The contribution of fluoride to the pathogenesis of eye diseases: molecular mechanisms and implications for public health
DT Waugh - International Journal of Environmental Research and …, 2019 - mdpi.com
This study provides diverse lines of evidence demonstrating that fluoride (F) exposure
contributes to degenerative eye diseases by stimulating or inhibiting biological pathways …
contributes to degenerative eye diseases by stimulating or inhibiting biological pathways …
[HTML][HTML] Transcriptomic behavior of genes associated with chromosome 21 aneuploidies in early embryo development
I Sanchez-Ribas, P Diaz-Gimeno, P Sebastián-León… - Fertility and sterility, 2019 - Elsevier
Objective To analyze how chromosome 21 (HSA21) ploidy affects global gene expression of
early human blastocysts. Design Prospective study. Setting University-affiliated in vitro …
early human blastocysts. Design Prospective study. Setting University-affiliated in vitro …