B-cell lymphomas are a group of heterogeneous neoplasms resulting from the clonal
expansion of mature B cells arrested at various stages of differentiation. Specifically, two …

Diffuse large B cell lymphoma (DLBCL) is a genetically highly heterogeneous disease. Yet,
to date, the vast majority of patients receive standardized frontline chemo-immune-therapy …

SMARCA4 encodes one of two mutually exclusive ATPase subunits in the BRG/BRM
associated factor (BAF) complex that is recruited by transcription factors (TFs) to drive …

Multimodal single-cell profiling methods can capture immune cell variations unfolding over
time at the molecular, cellular, and population levels. Transforming these data into biological …

The recently discovered APRO (anti-proliferative protein) family encodes a group of trans-
membrane glycoproteins and includes 6 members: TOB1, TOB2, BTG1, BTG2, BTG3 and …

Humoral immunity depends on the germinal center (GC) reaction where B cells are tightly
controlled for class-switch recombination and somatic hypermutation and finally generated …

Primary vitreoretinal lymphoma (PVRL) is a rare malignant lymphoma subtype with an
unfavorable prognosis due to frequent central nervous system (CNS) progression. Thus …

Overexpression of the anti-apoptotic protein BCL-2 is a key factor in the pathogenesis of
chronic lymphocytic leukemia (CLL) and is associated with poor clinical outcomes …

The determination of the genetic subtypes of primary CNS lymphoma (PCNSL) and their
relationship to differential chemo-immunotherapeutic response has not been established …

As a novel form of cell death, ferroptosis is mainly regulated by the accumulation of soluble
iron ions in the cytoplasm and the production of lipid peroxides and is closely associated …