Targeting NADPH oxidases in vascular pharmacology
A Schramm, P Matusik, G Osmenda, TJ Guzik - Vascular pharmacology, 2012 - Elsevier
Oxidative stress is a molecular dysregulation in reactive oxygen species (ROS) metabolism,
which plays a key role in the pathogenesis of atherosclerosis, vascular inflammation and …
which plays a key role in the pathogenesis of atherosclerosis, vascular inflammation and …
Glycation and antioxidants: hand in the glove of antiglycation and natural antioxidants
The non-enzymatic interaction of sugar and protein resulting in the formation of advanced
glycation end products responsible for cell signaling alterations ultimately leads to the …
glycation end products responsible for cell signaling alterations ultimately leads to the …
Natural products as promising drug candidates for the treatment of Alzheimer's disease: molecular mechanism aspect
N Ansari, F Khodagholi - Current neuropharmacology, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder to date, with no
curative or preventive therapy. Histopathological hallmarks of AD include deposition of β …
curative or preventive therapy. Histopathological hallmarks of AD include deposition of β …
Implication of caspase‐3 as a common therapeutic target for multineurodegenerative disorders and its inhibition using nonpeptidyl natural compounds
S Khan, K Ahmad, EMA Alshammari… - BioMed research …, 2015 - Wiley Online Library
Caspase‐3 has been identified as a key mediator of neuronal apoptosis. The present study
identifies caspase‐3 as a common player involved in the regulation of …
identifies caspase‐3 as a common player involved in the regulation of …
[HTML][HTML] Neuroprotective effects of allocryptopine-rich alkaloid extracts against oxidative stress-induced neuronal damage
Background Oxidative stress is a significant feature in the pathomechanism of
neurodegenerative diseases. Thus, the search for an effective and safe novel antioxidant …
neurodegenerative diseases. Thus, the search for an effective and safe novel antioxidant …
Protective effects of wheat germ protein isolate hydrolysates (WGPIH) against hydrogen peroxide-induced oxidative stress in PC12 cells
KX Zhu, X Guo, XN Guo, W Peng, HM Zhou - Food research international, 2013 - Elsevier
The protective effects of the enzymatic hydrolysates of wheat germ protein isolate against
the cytotoxicity and apoptosis produced by exposure to H 2 O 2 in PC12 cells were …
the cytotoxicity and apoptosis produced by exposure to H 2 O 2 in PC12 cells were …
Protective properties of Salvia lavandulifolia Vahl. essential oil against oxidative stress-induced neuronal injury
M Porres-Martínez, E González-Burgos… - Food and Chemical …, 2015 - Elsevier
Salvia lavandulifolia Vahl., known as “Spanish sage”, has potential value in dementia for its
sedative, antioxidant, anti-inflammatory and anticholinesterase properties. This work aimed …
sedative, antioxidant, anti-inflammatory and anticholinesterase properties. This work aimed …
Synthetic and Natural Bioactive Molecules in Balancing the Crosstalk among Common Signaling Pathways in Alzheimer's Disease: Understanding the Neurotoxic …
The structure and function of the brain greatly rely on different signaling pathways. The wide
variety of biological processes, including neurogenesis, axonal remodeling, the …
variety of biological processes, including neurogenesis, axonal remodeling, the …
Small molecule natural products and Alzheimer's disease
X Wu, H Cai, L Pan, G Cui, F Qin… - Current topics in …, 2019 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive and deadly neurodegenerative disease that is
characterized by memory loss, cognitive impairment and dementia. Several hypotheses …
characterized by memory loss, cognitive impairment and dementia. Several hypotheses …
[HTML][HTML] Inactivation of PI3K/Akt pathway and upregulation of PTEN gene are involved in daucosterol, isolated from Salvia sahendica, induced apoptosis in human …
MA Esmaeili, MM Farimani - South African Journal of Botany, 2014 - Elsevier
Ethnopharmacological relevance Salvia sahendica has been traditionally used for
antibacterial, anti-fungal, and anti-cancer purposes and treatment of dyspepsia in many …
antibacterial, anti-fungal, and anti-cancer purposes and treatment of dyspepsia in many …