Early T-cell precursor acute lymphoblastic leukemia: diagnosis, updates in molecular pathogenesis, management, and novel therapies
C Sin, PM Man - Frontiers in oncology, 2021 - frontiersin.org
Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL) is a distinct subtype of T
lymphoblastic leukemia (T-ALL) identified in 2009, due to its unique immunophenotypic and …
lymphoblastic leukemia (T-ALL) identified in 2009, due to its unique immunophenotypic and …
CAR T-cell immunotherapy treating T-ALL: Challenges and opportunities
A Ren, X Tong, N Xu, T Zhang, F Zhou, H Zhu - Vaccines, 2023 - mdpi.com
T-cell acute lymphoblastic leukemia (T-ALL), a form of T-cell malignancy, is a typically
aggressive hematological malignancy with high rates of disease relapse and a poor …
aggressive hematological malignancy with high rates of disease relapse and a poor …
Outcome of T‐cell acute lymphoblastic leukemia/lymphoma: focus on near‐ETP phenotype and differential impact of nelarabine
K Morita, N Jain, H Kantarjian… - American journal of …, 2021 - Wiley Online Library
Early T‐cell precursor acute lymphoblastic leukemia/lymphoma (ETP‐ALL/LBL) is
characterized by a distinct immunophenotype (CD1a‐negative, CD8‐negative, CD5 …
characterized by a distinct immunophenotype (CD1a‐negative, CD8‐negative, CD5 …
Immunohistochemistry innovations for diagnosis and tissue-based biomarker detection
N Sukswai, JD Khoury - Current hematologic malignancy reports, 2019 - Springer
Abstract Purpose of Review Immunohistochemistry is an integral technique for tissue-based
diagnostics and biomarker detection with broad worldwide adoption. Advances in core …
diagnostics and biomarker detection with broad worldwide adoption. Advances in core …
CD123 as a biomarker in hematolymphoid malignancies: principles of detection and targeted therapies
Simple Summary CD123 is overexpressed in multiple hematologic malignancies. Advances
in CD123-targeted therapies over the past decade have positioned this molecule as an …
in CD123-targeted therapies over the past decade have positioned this molecule as an …
Early precursor T-cell acute lymphoblastic leukemia: current paradigms and evolving concepts
O Castaneda Puglianini… - Therapeutic Advances …, 2020 - journals.sagepub.com
Early precursor T cell-acute lymphoblastic leukemia (ETP-ALL) is a rare entity characterized
by chemo-resistance and a paucity of data regarding optimal management. We review here …
by chemo-resistance and a paucity of data regarding optimal management. We review here …
Applications and efficiency of flow cytometry for leukemia diagnostics
MI Del Principe, E De Bellis, C Gurnari… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Multiparametric flow cytometry immunophenotype (MFCI) plays a crucial role in
the diagnosis of acute leukemia (AL). Through the comprehensive assessment of surface …
the diagnosis of acute leukemia (AL). Through the comprehensive assessment of surface …
In Silico Integration of Transcriptome and Interactome Predicts an ETP-ALL-Specific Transcriptional Footprint that Decodes its Developmental Propensity
S Mukherjee, A Kar, P Paul, S Dey… - Frontiers in Cell and …, 2022 - frontiersin.org
Early T precursor acute lymphoblastic leukemia (ETP-ALL) exhibits poor clinical outcomes
and high relapse rates following conventional chemotherapeutic protocols. Extensive …
and high relapse rates following conventional chemotherapeutic protocols. Extensive …
Clinicopathologic features and outcomes of acute leukemia harboring PICALM:: MLLT10 fusion
J Wang, W Zhang, X Xu, A Buglioni, P Li, X Chen, Y Liu… - Human Pathology, 2024 - Elsevier
The PICALM:: MLLT10 fusion is a rare but recurrent cytogenetic abnormality in acute
leukemia, with limited clinicopathologic and outcome data available. Herein, we analyzed …
leukemia, with limited clinicopathologic and outcome data available. Herein, we analyzed …
B‐cell lymphoma/leukaemia 11B (BCL11B) expression status helps distinguish early T‐cell precursor acute lymphoblastic leukaemia/lymphoma (ETP‐ALL/LBL) from …
H Fang, W Wang, S El Hussein, K Morita… - British Journal of …, 2021 - Wiley Online Library
B‐cell lymphoma/leukaemia 11B (BCL11B) is an essential transcription factor for T‐cell
lineage commitment and maturation. We investigated BCL11B expression by …
lineage commitment and maturation. We investigated BCL11B expression by …