The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases
An intense, stereotyped inflammatory response occurs in response to ischaemic and non-
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …
The NLRP3 inflammasome in acute myocardial infarction
The heart is extremely sensitive to ischaemic injury. During an acute myocardial infarction
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
(AMI) event, the injury is initially caused by reduced blood supply to the tissues, which is …
Inflammation–cause or consequence of heart failure or both?
S Van Linthout, C Tschöpe - Current heart failure reports, 2017 - Springer
Abstract Purpose of Review With the intention to summarize the currently available evidence
on the pathophysiological relevance of inflammation in heart failure, this review addresses …
on the pathophysiological relevance of inflammation in heart failure, this review addresses …
Chronic heart failure and inflammation: what do we really know?
SA Dick, S Epelman - Circulation research, 2016 - Am Heart Assoc
As a greater proportion of patients survive their initial cardiac insult, medical systems
worldwide are being faced with an ever-growing need to understand the mechanisms …
worldwide are being faced with an ever-growing need to understand the mechanisms …
Role of innate and adaptive immune mechanisms in cardiac injury and repair
Despite the advances that have been made in developing new therapeutics, cardiovascular
disease remains the leading cause of worldwide mortality. Therefore, understanding the …
disease remains the leading cause of worldwide mortality. Therefore, understanding the …
Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes
Background Impaired wound healing is the most common and significant complication of
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …
IL-17 and Th17 cells in atherosclerosis: subtle and contextual roles
Atherosclerosis is a chronic inflammatory arterial disease driven by both innate and adaptive
immune responses to modified lipoproteins and components of the injured vascular wall …
immune responses to modified lipoproteins and components of the injured vascular wall …
Цитокины в патогенезе и лечении заболеваний человека
АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …
процессов, защитных реакций организма и в патогенезе иммунопатологических …
An interleukin-23-interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis
Although commensal flora is involved in the regulation of immunity, the interplay between
cytokine signaling and microbiota in atherosclerosis remains unknown. We found that …
cytokine signaling and microbiota in atherosclerosis remains unknown. We found that …
The dynamic interplay between cardiac inflammation and fibrosis
TP Thomas, LA Grisanti - Frontiers in physiology, 2020 - frontiersin.org
Heart failure is a leading cause of death worldwide. While there are multiple etiologies
contributing to the development of heart failure, all cause result in impairments in cardiac …
contributing to the development of heart failure, all cause result in impairments in cardiac …