Long-acting parenteral drug delivery systems for the treatment of chronic diseases

AB Jindal, AR Bhide, S Salave, D Rana… - Advanced Drug Delivery …, 2023 - Elsevier
The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

Lipid nanoparticles functionalized with antibodies for anticancer drug therapy

AC Marques, PC Costa, S Velho, MH Amaral - Pharmaceutics, 2023 - mdpi.com
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In
the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs) …

Biomaterial‐based gene therapy

Y Yu, Y Gao, L He, B Fang, W Ge, P Yang, Y Ju… - MedComm, 2023 - Wiley Online Library
Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

In vitro prostate cancer treatment via CRISPR‐Cas9 gene editing facilitated by polyethyleneimine‐derived graphene quantum dots

B Lee, K Gries, AR Valimukhametova… - Advanced Functional …, 2023 - Wiley Online Library
Abstract CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)‐Cas9
(CRISPR associated protein 9) is a programmable gene editing tool with a promising …

Cellular Trafficking of Nanotechnology‐Mediated mRNA Delivery

P Huang, H Deng, C Wang, Y Zhou… - Advanced …, 2024 - Wiley Online Library
Messenger RNA (mRNA)‐based therapy has emerged as a powerful, safe, and rapidly
scalable therapeutic approach that involves technologies for both mRNA itself and the …

[HTML][HTML] Targeted drug delivery systems for elemene in cancer therapy: The story thus far

H Tian, F Zhao, Q Qi, B Yue, B Zhai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Elemene (ELE) is a group of broad-spectrum anticancer active ingredients with low toxicity
extracted from traditional Chinese medicines (TCMs), such as Curcumae Rhizoma and …

Delivery of RNAs to specific organs by lipid nanoparticles for gene therapy

K Godbout, JP Tremblay - Pharmaceutics, 2022 - mdpi.com
Gene therapy holds great promise in the treatment of genetic diseases. It is now possible to
make DNA modifications using the CRISPR system. However, a major problem remains: the …

Recent advances in nanoparticle-mediated co-delivery system: A promising strategy in medical and Agricultural Field

M Li, X Sun, M Yin, J Shen, S Yan - International Journal of Molecular …, 2023 - mdpi.com
Drug and gene delivery systems mediated by nanoparticles have been widely studied for life
science in the past decade. The application of nano-delivery systems can dramatically …

[HTML][HTML] Microfluidic platforms in diagnostic of ovarian cancer

FD Moghaddam, D Dadgar, Y Esmaeili… - Environmental …, 2023 - Elsevier
The most important reason for death from ovarian cancer is the late diagnosis of this
disease. The standard treatment of ovarian cancer includes surgery and chemotherapy …

Selective organ targeting nanoparticles: from design to clinical translation

J Li, H Wang - Nanoscale Horizons, 2023 - pubs.rsc.org
Targeting nanoparticle is a very promising therapeutic approach that can precisely target
specific sites to treat diseases. Research on nanoscale drug delivery systems has made …