The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …

DNA-dependent RNA polymerases (Pols) transfer the genetic information stored in genomic
DNA to RNA in all organisms. In eukaryotes, the typical products of nuclear Pol I, Pol II, and …

Summary RNA polymerase II (RNAPII) transcription involves initiation from a promoter,
transcriptional elongation through the gene, and termination in the terminator region. In …

Replication forks terminate at TERs and telomeres. Forks that converge or encounter
transcription generate topological stress. Combining genetics, genomics, and transmission …

Cellular homeostasis requires the coordination of several machineries concurrently
engaged in the DNA. Wide-spread transcription can interfere with other processes, and …

Transcriptional pause is essential for all types of termination. In this single-molecule study
on bacterial Rho factor-dependent terminators, we confirm that the three Rho-dependent …

Transcription of tRNA genes by RNA polymerase III (RNAPIII) is tuned by signaling
cascades. The emerging notion of differential tRNA gene regulation implies the existence of …

Nucleic acid sensors survey subcellular compartments for atypical or mislocalized RNA or
DNA, ultimately triggering innate immune responses. Retinoic acid-inducible gene-I (RIG-I) …

Sen1 is an essential helicase for factor-dependent transcription termination in
Saccharomyces cerevisiae, whose molecular-motor mechanism has not been well …

Transcription termination is the final step of a transcription cycle, which induces the release
of the transcript at the termination site and allows the recycling of the polymerase for the next …