The eukaryotic cell is a bustling collection of macromolecules acting cooperatively to
mediate the functions required for cell viability. Specific, context-dependent and tightly …

Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player
in chromosome segregation. As part of a macromolecular complex known as the …

Cellular responses to environmental cues involve the mobilization of GTPases, protein
kinases and phosphoprotein phosphatases. The spatial organization of these signalling …

Protein Ser/Thr phosphatase-1 (PP1) catalyzes the majority of eukaryotic protein
dephosphorylation reactions in a highly regulated and selective manner. Recent studies …

Ser/Thr protein phosphatase 1 (PP1) is a single‐domain hub protein with nearly 200
validated interactors in vertebrates. PP1‐interacting proteins (PIPs) are ubiquitously …

Maintaining genome integrity during cell division requires regulated interactions between
chromosomes and spindle microtubules. To ensure that daughter cells inherit the correct …

Regulated interactions between kinetochores and spindle microtubules are essential to
maintain genomic stability during chromosome segregation. The Aurora B kinase …

The ubiquitous serine/threonine protein phosphatase 1 (PP1) regulates diverse, essential
cellular processes such as cell cycle progression, protein synthesis, muscle contraction …

When the nucleolus disassembles during open mitosis, many nucleolar proteins and RNAs
associate with chromosomes, establishing a perichromosomal compartment coating the …

This review traces the historical origins and conceptual developments leading to the current
state of knowledge of the three superfamilies of protein Ser/Thr phosphatases.'PR …