Protein function is constrained by the three-dimensional structure but is delineated by its
dynamics. This framework must satisfy specificity of function along with adaptability to …

Coarse‐grained normal mode analyses of protein dynamics rely on the idea that the
geometry of a protein structure contains enough information for computing its fluctuations …

Large macromolecules, including proteins and their complexes, very often adopt multiple
conformations. Some of them can be seen experimentally, for example with x-ray …

The intrinsic dynamics of proteins can be used to analyze the thermal fluctuations, functional
modes, collective motions, and correlated movements. The principal component analysis …

In light of the recent very rapid progress in protein structure prediction, accessing the
multitude of functional protein states is becoming more central than ever before. Indeed …