[HTML][HTML] PSF and p54nrb/NonO–multi-functional nuclear proteins

Y Shav-Tal, D Zipori - FEBS letters, 2002 - Elsevier
Proteins are often referred to in accordance with the activity with which they were first
associated or the organelle in which they were initially identified. However, a variety of …

NONO and tumorigenesis: More than splicing

P Feng, L Li, T Deng, Y Liu, N Ling… - Journal of cellular …, 2020 - Wiley Online Library
The non‐POU domain‐containing octamer‐binding protein NONO/p54nrb, which belongs to
the Drosophila behaviour/human splicing (DBHS) family, is a multifunctional nuclear protein …

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold

GJ Knott, CS Bond, AH Fox - Nucleic acids research, 2016 - academic.oup.com
Nuclear proteins are often given a concise title that captures their function, such as
'transcription factor,''polymerase'or 'nuclear-receptor.'However, for members of the …

The fate of dsRNA in the nucleus: a p54nrb-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs

Z Zhang, GG Carmichael - Cell, 2001 - cell.com
How do cells discriminate between selectively edited mRNAs that encode new protein
isoforms, and dsRNA-induced, promiscuously edited RNAs that encode nonfunctional …

Alu element‐mediated gene silencing

LL Chen, JN DeCerbo, GG Carmichael - The EMBO journal, 2008 - embopress.org
The Alu elements are conserved∼ 300‐nucleotide‐long repeat sequences that belong to
the SINE family of retrotransposons found abundantly in primate genomes. Pairs of inverted …

Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions

NR Hwang, SH Yim, YM Kim, J Jeong… - Biochemical …, 2009 - portlandpress.com
Knowledge of the cellular targets of ROS (reactive oxygen species) and their regulation is an
essential prerequisite for understanding ROS-mediated signalling. GAPDH (glyceraldehyde …

PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors

M Mathur, PW Tucker, HH Samuels - Molecular and Cellular …, 2001 - Taylor & Francis
Members of the type II nuclear hormone receptor subfamily (eg, thyroid hormone receptors
[TRs], retinoic acid receptors, retinoid X receptors [RXRs], vitamin D receptor, and the …

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion

C Rajesh, DK Baker, AJ Pierce… - Nucleic acids …, 2011 - academic.oup.com
DNA double-stranded breaks (DSBs) are among the most severe forms of DNA damage and
responsible for chromosomal translocations that may lead to gene fusions. The RAD51 …

PSF and p54nrb bind a conserved stem in U5 snRNA

R Peng, BT Dye, I Pérez, DC Barnard, AB Thompson… - Rna, 2002 - cambridge.org
PTB-associated splicing factor (PSF) has been implicated in both early and late steps of pre-
mRNA splicing, but its exact role in this process remains unclear. Here we show that PSF …

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription

S Landeras-Bueno, N Jorba, M Perez-Cidoncha… - PLoS …, 2011 - journals.plos.org
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral
genome transcription and replication in the nucleus of infected cells. We recently carried out …