Antibiotic-induced decreases in the levels of microbial-derived short-chain fatty acids correlate with increased gastrointestinal colonization of Candida albicans
Candida albicans is the fourth most common cause of systemic nosocomial infections,
posing a significant risk in immunocompromised individuals. As the majority of systemic C …
posing a significant risk in immunocompromised individuals. As the majority of systemic C …
Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation
Candida albicans remains the main etiologic agent of candidiasis, the most common fungal
infection and now the third most frequent infection in US hospitals. The scarcity of antifungal …
infection and now the third most frequent infection in US hospitals. The scarcity of antifungal …
Mechanisms of action of antimicrobial peptides ToAP2 and NDBP-5.7 against Candida albicans planktonic and biofilm cells
J do Nascimento Dias, C de Souza Silva… - Scientific reports, 2020 - nature.com
Candida albicans is a major cause of human infections, ranging from relatively simple to
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …
Yeast and filaments have specialized, independent activities in a zebrafish model of Candida albicans infection
BG Seman, JL Moore, AK Scherer, BA Blair… - Infection and …, 2018 - Am Soc Microbiol
Candida albicans dimorphism is a crucial virulence factor during invasive candidiasis
infections, which claim the lives of nearly one-half of those afflicted. It has long been …
infections, which claim the lives of nearly one-half of those afflicted. It has long been …
Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections
X Jin, X Hou, X Wang, M Zhang, J Chen, M Song… - Cell Chemical …, 2023 - cell.com
Filamentation is an important virulence factor of the pathogenic fungus Candida albicans.
The abolition of Candida albicans hyphal formation by disrupting sterol synthesis is an …
The abolition of Candida albicans hyphal formation by disrupting sterol synthesis is an …
Small molecules restore azole activity against drug-tolerant and drug-resistant Candida isolates
Each year, fungi cause more than 1.5 billion infections worldwide and have a devastating
impact on human health, particularly in immunocompromised individuals or patients in …
impact on human health, particularly in immunocompromised individuals or patients in …
Plasma activated Ezhangfeng Cuji as innovative antifungal agent and its inactivation mechanism
L Lin, Y Zhuo, Q Dong, C Yang, C Cheng, T Liu - AMB Express, 2023 - Springer
Candida albicans is a highly drug-resistant fungus for which new treatments are urgently
needed due to the lack of clinically effective options. In this study, we evaluated the …
needed due to the lack of clinically effective options. In this study, we evaluated the …
A novel approach: targeting virulence factors of Candida albicans with essential oil components
AMA Shaban, H Darmani - Journal of Applied Microbiology, 2024 - academic.oup.com
Aims Focusing on phytochemicals to target the virulence factors of Candida albicans is a
promising avenue for novel antifungal compounds. Given the limited prior research on …
promising avenue for novel antifungal compounds. Given the limited prior research on …
The effect of benzyl isothiocyanate on Candida albicans growth, cell size, morphogenesis, and ultrastructure
C Pereira, AM Calado, AC Sampaio - World Journal of Microbiology and …, 2020 - Springer
Candida albicans is a commensal yeast that may become pathogenic and even lethal to the
host. Over the last few decades, antifungal resistance has increased, promoting screening of …
host. Over the last few decades, antifungal resistance has increased, promoting screening of …
Nanoemulsion as an effective treatment against human-pathogenic fungi
A Garcia, YY Fan, S Vellanki, EY Huh, DF Vanegas… - MSphere, 2019 - Am Soc Microbiol
Infections triggered by pathogenic fungi cause a serious threat to the public health care
system. In particular, an increase of antifungal drug-resistant fungi has resulted in difficulty in …
system. In particular, an increase of antifungal drug-resistant fungi has resulted in difficulty in …