Targeted protein degradation (TPD) is an emerging therapeutic modality with the potential to
tackle disease-causing proteins that have historically been highly challenging to target with …

The development of new biodegradable plastic materials from renewable sources is a major
challenge for plastic industries to provide sustainable alternatives to petroleum plastic. Bio …

The anticancer agent indisulam inhibits cell proliferation by causing degradation of RBM39,
an essential mRNA splicing factor. Indisulam promotes an interaction between RBM39 and …

Two decades into the twenty-first century, a confluence of breakthrough technologies
wielded at the molecular level is presenting biologists with unique opportunities to unravel …

Plants are equipped with the capacity to respond to a large number of diverse signals, both
internal ones and those emanating from the environment, that are critical to their survival …

The plant circadian clock allows organisms to anticipate the predictable changes in the
environment by adjusting their developmental and physiological traits. In the last few years …

Highlights•Programmed cell death (PCD) is an integral part of plant development and
disease.•Developmental PCD (dPCD) is prepared during the cellular differentiation of …

Plant U-box type E3 ubiquitin ligases (PUBs) are well known for their functions in a variety of
stress responses, including immune responses and the adaptation to abiotic stresses. First …

The directional transport of auxin, known as polar auxin transport (PAT), allows asymmetric
distribution of this hormone in different cells and tissues. This system creates local auxin …

Content Summary 41 I. Introduction 41 II. Historical outline 42 III. Recent developments 43
IV. Towards an integrative concept for cytokinin receptor signaling 48 Acknowledgements 51 …