The COVID-19 pandemic has major implications for blood transfusion. There are uncertain
patterns of demand, and transfusion institutions need to plan for reductions in donations and …

Platelet transfusions are commonly administered for the prevention or treatment of bleeding
in patients with acquired thrombocytopenia across a range of clinical contexts. Recent data …

Due to circumstances such as increased demand and an aging donor pool, the likelihood of
critical platelet shortages is increasing. The platelet supply could be improved through the …

Introduction A pandemic coronavirus, SARS‐CoV‐2, causes COVID‐19, a potentially life‐
threatening respiratory disease. Patients with cancer may have compromised immunity due …

Cryopreservation of platelets, at− 80° C with 5–6% DMSO, results in externalisation of
phosphatidylserine and the formation of extracellular vesicles (EVs), which may mediate …

Background There is renewed interest in the use of whole blood (WB) for the resuscitation of
trauma patients. Platelet function in stored WB compared to platelet concentrates is not well …

Platelets are anucleate blood cells produced from megakaryocytes predominantly in the
bone marrow and released into blood circulation at a healthy count of 150,000–400, 00 per …

Background Human platelets (PLT) and PLT-extracellular vesicles (PEV) released upon
thrombin activation express receptors that interact with tumour cells and, thus, can serve as …

Abstract Background The Netherlands Armed Forces (NLAF) are using− 80° C deep‐frozen
thrombocyte concentrate (DTC) since 2001. The aim of this study is to investigate the effect …

Storage requirements and outdating of platelets represent a continued challenge for blood
banks. These hurdles are confounded for rural area hospitals or in military deployments …