Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches
K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …
therapy, currently, there is no significant progress in the treatment of different types of brain …
Wireless on-demand drug delivery
SM Mirvakili, R Langer - Nature Electronics, 2021 - nature.com
Wireless on-demand drug delivery systems exploit exogenous stimuli—acoustic waves,
electric fields, magnetic fields and electromagnetic radiation—to trigger drug carriers. The …
electric fields, magnetic fields and electromagnetic radiation—to trigger drug carriers. The …
Magnetic torque–driven living microrobots for increased tumor infiltration
Biohybrid bacteria–based microrobots are increasingly recognized as promising externally
controllable vehicles for targeted cancer therapy. Magnetic fields in particular have been …
controllable vehicles for targeted cancer therapy. Magnetic fields in particular have been …
Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness
While most cancer nanomedicine is designed to eliminate cancer, the nanomaterial per se
can lead to the formation of micrometre-sized gaps in the blood vessel endothelial walls …
can lead to the formation of micrometre-sized gaps in the blood vessel endothelial walls …
Self-powered, light-controlled, bioresorbable platforms for programmed drug delivery
Degradable polymer matrices and porous scaffolds provide powerful mechanisms for
passive, sustained release of drugs relevant to the treatment of a broad range of diseases …
passive, sustained release of drugs relevant to the treatment of a broad range of diseases …
Nanoparticles' interactions with vasculature in diseases
JK Tee, LX Yip, ES Tan, S Santitewagun… - Chemical Society …, 2019 - pubs.rsc.org
The ever-growing use of inorganic nanoparticles (NPs) in biomedicine provides an exciting
approach to develop novel imaging and drug delivery systems, owing to the ease with which …
approach to develop novel imaging and drug delivery systems, owing to the ease with which …
[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain
LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …
studied extensively during the past 20 years for numerous biomedical applications. The …
Spatiotemporal control of CRISPR/Cas9 gene editing
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein
9 (CRISPR/Cas9) gene editing technology, as a revolutionary breakthrough in genetic …
9 (CRISPR/Cas9) gene editing technology, as a revolutionary breakthrough in genetic …
Engineered materials for in vivo delivery of genome-editing machinery
Genome-editing technologies, such as CRISPR–Cas9, are promising for treating otherwise
incurable genetic diseases. Great progress has been made for ex vivo genome editing; …
incurable genetic diseases. Great progress has been made for ex vivo genome editing; …
Biologically targeted magnetic hyperthermia: Potential and limitations
Hyperthermia, the mild elevation of temperature to 40–43° C, can induce cancer cell death
and enhance the effects of radiotherapy and chemotherapy. However, achievement of its full …
and enhance the effects of radiotherapy and chemotherapy. However, achievement of its full …