[HTML][HTML] Tocotrienols modulate a life or death decision in cancers

SY Tham, HS Loh, CW Mai, JY Fu - International journal of molecular …, 2019 - mdpi.com
Malignancy often arises from sophisticated defects in the intricate molecular mechanisms of
cells, rendering a complicated molecular ground to effectively target cancers. Resistance …

Phytochemicals from Calophyllum canum Hook f. ex T. Anderson and their neuroprotective effects

MA Lizazman, VYM Jong, PF Chua, WK Lim… - Natural Product …, 2023 - Taylor & Francis
Previous phytochemical investigations reported that Calophyllum spp have biosynthesized a
wide range of bioactive phenolics such as xanthones and coumarins. The phytochemical …

Drug‐like dietary vanilloids induce anticancer activity through proliferation inhibition and regulation of bcl‐related apoptotic proteins

CW Mai, YB Kang, VD Nadarajah… - Phytotherapy …, 2018 - Wiley Online Library
In this study, a series of 20 structurally similar vanilloids (Vn) were tested for their
antiproliferative effects against 12 human cancer cells: human breast (MCF‐7 and MDA‐MB …

[HTML][HTML] In silico prediction of flavan-3-ol as a bioactive compound of Calophyllum macrophyllum as a potential drug against angiostrongylus eosinophilic meningitis

M Hambal, F Frengki, WE Sari, H Vanda - Veterinary World, 2022 - ncbi.nlm.nih.gov
Materials and Methods: Pharmacokinetic and toxicological data were analyzed and
supported by the server http://www. swissadme. ch/index. php and https://tox-new. charite …

[PDF][PDF] A review of the effects of Calophyllum spp. on cancer cells

M Kilus, NA Samad, S Daud - Journal of Angioterpay, 2023 - researchgate.net
Abstract Background: The genus Calophyllum and its species has received great research
interest for their phytochemical content and therapeutic potential. Said interest was sparked …

Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells

YS Chong, CW Mai, CO Leong… - Cutaneous and Ocular …, 2018 - Taylor & Francis
Purpose: Dysfunction of the microRNA (miRNA)-processing enzyme DICER1 and Alu RNA
accumulation are linked to the pathogenesis of age-related macular degeneration (AMD) …

Calaxanthones AC, three new xanthones from the roots of Calophyllum calaba and the cytotoxicity

F Laopian, S Kaennakam, K Rassamee… - Natural product …, 2019 - Taylor & Francis
Three new xanthones, named calaxanthones AC (1–3), along with 17 known xanthones (4–
20) were isolated from the roots of Calophyllum calaba. Their structures were determined by …

Heterocyclic-Based Analogues against Sarcine-Ricin Loop RNA from Escherichia coli: In Silico Molecular Docking Study and Machine Learning Classifiers

S Sharma, R Choubey, M Gupta… - Medicinal Chemistry, 2024 - ingentaconnect.com
> Background: Heterocyclic-based drugs have strong bioactivities, are active
pharmacophores, and are used to design several antibacterial drugs. Due to the diverse …

[PDF][PDF] Comparison of extraction techniques for three Calophyllum species and their antioxidant activity

SN Ramli, NI Aminudin, F Ahmad… - Malaysian Journal of …, 2019 - mjas.analis.com.my
Calophyllum is a pan-tropical genus belonging to the Guttiferae family and is known in
Malaysia as 'bintangor'. There has been continual interest to further investigate the …

4-Alkylcoumarins and a phloroglucinol from the stem bark of Calophyllum gracilentum

CK Lim, YP Ham, LQ Lim, VYM Jong - Phytochemistry Letters, 2019 - Elsevier
Three new 4-alkylcoumarins, gracilenins A–C (1-3) and a new phloroglucinol, gracilenol (4),
along with two known compounds, euxanthone and friedelin were isolated from the stem …