Exercise ventilation (V′ E) relative to carbon dioxide output (V′ CO2) is particularly
relevant to patients limited by the respiratory system, eg those with chronic obstructive …

In the last American Thoracic Society (ATS) statement, dyspnea was defined as “a subjective
experience of breathing discomfort that consists of qualitatively distinct sensations that vary …

Exertional dyspnea is present across the spectrum of chronic obstructive pulmonary disease
(COPD) severity. However, without realizing it themselves, patients may decrease daily …

Background The relevance of screening for airway obstruction in subjects not complaining of
COPD symptoms may depend on the definition of airway obstruction. Response to exercise …

Background Main risk factor for the development of chronic obstructive pulmonary disease
(COPD) is smoking, although only less than 1/3 of smokers develop clinically manifest …

Background We aimed to study the adverse outcomes of symptomatic and asymptomatic
non-obstructed individuals and those with mild COPD longitudinally in participants from …

Heightened oxidative stress is implicated in the progressive impairment of skeletal muscle
vascular and mitochondrial function in chronic obstructive pulmonary disease (COPD) …

In 2020, COPD was the third leading cause of death worldwide. Lung function is central for
the diagnosis of this disease, and COPD severity is still partially classified based on airflow …

Exertional dyspnea, a key complaint of patients with chronic obstructive pulmonary disease
(COPD), ultimately reflects an increased inspiratory neural drive to breathe. In non …

There is growing recognition that a sizable fraction of COPD patients with forced expiratory
volume in one second (FEV1)/forced vital capacity ratio below the lower limit of normal but …