The 2009 World Health Organization report on global health risks identifies hypertension,
smoking, raised glucose, physical inactivity, obesity and dyslipidaemia, in that order, as …

Objective To quantify the unintended effects of statins according to type, dose, and duration
of use. Design Prospective open cohort study using routinely collected data. Setting 368 …

Objective To evaluate the performance of the QRISK2 score for predicting 10-year
cardiovascular disease in an independent UK cohort of patients from general practice …

Cardiovascular disease (CVD) risk screening is performed by multivariate methods relying
on calculators derived from the Framingham study, other epidemiological studies or primary …

We briefly review here the evidence that the NHS Health Checks (NHSHC) programme
represents an ineffective strategy and is currently wasting scarce resources. The NHSHC …

Background: Temporal pathways of known associations between overweight and poor
health-related quality of life (HRQoL) in adolescents remain poorly documented. This study …

Objective To derive and validate risk algorithms so that the risks of four clinical outcomes
associated with statin use can be estimated for individual patients. Design Prospective open …

Background The updated (2014) National Institute for Health and Care Excellence (NICE)
guideline lowered the recommended threshold for statin prescription from 20% to 10% 10 …

A population-based programme of health checks was introduced for adults in England in
2011 for the primary prevention of cardiovascular diseases (CVD) and risk factors …

There is clearly an association between obstructive sleep apnoea (OSA) and vascular
disease (Marin et al. 2005; Gottlieb et al. 2010). Much vascular disease remains …