Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections

P Zimmermann, N Curtis - Archives of disease in childhood, 2021 - adc.bmj.com
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …

A comprehensive review of COVID-19 virology, vaccines, variants, and therapeutics

L Forchette, W Sebastian, T Liu - Current medical science, 2021 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of
the coronavirus disease 2019 (COVID-19), has caused more than 179 million infections and …

[HTML][HTML] Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19)

DG Ahn, HJ Shin, MH Kim, S Lee, HS Kim… - … of microbiology and …, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness
such as pneumonia and lung failure, was first reported in Wuhan, the capital of Hubei …

Molecular mechanism for antibody-dependent enhancement of coronavirus entry

Y Wan, J Shang, S Sun, W Tai, J Chen, Q Geng… - Journal of …, 2020 - Am Soc Microbiol
Antibody-dependent enhancement (ADE) of viral entry has been a major concern for
epidemiology, vaccine development, and antibody-based drug therapy. However, the …

Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation

MH Cheng, S Zhang, RA Porritt… - Proceedings of the …, 2020 - National Acad Sciences
Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is a
newly recognized condition in children with recent severe acute respiratory syndrome …

Covid‐19 and dengue: double punches for dengue‐endemic countries in Asia

H Harapan, M Ryan, B Yohan… - Reviews in medical …, 2021 - Wiley Online Library
Summary The coronavirus disease 2019 (Covid‐19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is an international public health crisis …

Selenium biofortification in the 21st century: status and challenges for healthy human nutrition

M Schiavon, S Nardi, F Dalla Vecchia, A Ertani - Plant and soil, 2020 - Springer
Abstract Background Selenium (Se) is an essential element for mammals and its deficiency
in the diet is a global problem. Plants accumulate Se and thus represent a major source of …

I mmunosenescence and inflammaging: risk factors of severe COVID-19 in older people

AJ Pietrobon, FME Teixeira, MN Sato - Frontiers in immunology, 2020 - frontiersin.org
Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Antiviral neutralizing antibodies: from in vitro to in vivo activity

DR Burton - Nature Reviews Immunology, 2023 - nature.com
Neutralizing antibodies (nAbs) are being increasingly used as passive antiviral reagents in
prophylactic and therapeutic modalities and to guide viral vaccine design. In vivo, nAbs can …