The onset of crystal nucleation was studied for seeded semibatch experiments in aqueous
solutions in which either the feed rate, the seed size, or seed amount was varied. The results …

Batch and semi-batch crystallization experiments were performed in aqueous solutions for
the three anhydrous polymorphs of calcium carbonate vaterite, aragonite and calcite to …

As continuous manufacturing is evolving in the pharmaceutical industry, continuous filtration
has emerged as a bottleneck for connecting the crystallization of the active pharmaceutical …

The isolation and further treatment of particles generated in a crystallization process is
dependent on their size and shape. The work presented here analyzes the filtration …

The solvent-mediated crystal morphologies of the α and β polymorphic forms of l-glutamic
acid are presented. This work applies a digital mechanistically based workflow that …

A new process consisting of a combination of crystallization, milling, and dissolution stages
is presented. At first, a mathematical model for the different unit operations, as well as their …

Crystallization can be regarded as a self-assembly process in which randomly organized
molecules in a fluid come together to form an ordered three-dimensional molecular array …

Particle size and size distribution (PSD) are two crucial attributes for both particulate and
formulated products, particularly in the pharmaceutical industry. The control of the two …

In this work, thorough experimental characterization and theoretical investigation for the
quantitative description of the breakage of needlelike crystals of βl-glutamic acid in a …

Nowadays, it is common to analyze crystallization processes and crystalline products using
two-dimensional image analysis. Various techniques exist but they are not fundamentally …