Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Targeting protein kinases in central nervous system disorders

LK Chico, LJ Van Eldik, DM Watterson - Nature reviews Drug discovery, 2009 - nature.com
Protein kinases are a growing drug target class in disorders in peripheral tissues, but the
development of kinase-targeted therapies for central nervous system (CNS) diseases …

beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity

NN Okoye, DL Ajaghaku, HN Okeke… - Pharmaceutical …, 2014 - Taylor & Francis
Abstract Context: Alstonia boonei De Wild (Apocyanaceae) is used in ethnomedicine for the
management of malaria, ulcer, rhematic pain, toothache, and inflammatory disorders …

α-Amyrin and β-Amyrin Isolated from Celastrus hindsii Leaves and Their Antioxidant, Anti-Xanthine Oxidase, and Anti-Tyrosinase Potentials

TD Viet, TD Xuan, LH Anh - Molecules, 2021 - mdpi.com
Celastrus hindsii is a popular medicinal plant in Vietnam and Southeast Asian countries as
well as in South America. In this study, an amount of 12.05 g of an α-amyrin and β-amyrin …

Endogenous opiates and behavior: 2005

RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Antioxidant, α-Amylase and α-Glucosidase Inhibitory Activities and Potential Constituents of Canarium tramdenum Bark

NV Quan, TD Xuan, HD Tran, NTD Thuy, LT Trang… - Molecules, 2019 - mdpi.com
The fruits of Canarium tramdenum are commonly used as foods and cooking ingredients in
Vietnam, Laos, and the southeast region of China, whilst the leaves are traditionally used for …

Forest biorefinery: Potential of poplar phytochemicals as value-added co-products

RK Devappa, SK Rakshit, RFH Dekker - Biotechnology advances, 2015 - Elsevier
The global forestry industry after experiencing a market downturn during the past decade
has now aimed its vision towards the integrated biorefinery. New business models and …

Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice

MRA Rodrigues, LKS Kanazawa… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia officinalis L. has been used as a
traditional herbal medicine for gastric disturbances and inflammatory processes. This study …

Ethnopharmacological Significance of Eclipta alba (L.) Hassk. (Asteraceae)

R Jahan, A Al-Nahain, S Majumder… - International scholarly …, 2014 - Wiley Online Library
Eclipta alba can be found growing wild in fallow lands of Bangladesh where it is considered
as a weed by farmers. Traditional medicinal systems of the Indian subcontinent countries as …

A possible mechanism for anxiolytic and antidepressant effects of alpha-and beta-amyrin from Protium heptaphyllum (Aubl.) March

GF Aragão, LMV Carneiro, APF Junior, LC Vieira… - Pharmacology …, 2006 - Elsevier
In the present study, we examined the anxiolytic and antidepressant effects of the mixture of
alpha-and beta-amyrin (AMY), pentacyclic triterpenes isolated from the stem bark resin of …