Inflammation subtypes and translating inflammation-related genetic findings in schizophrenia and related psychoses: a perspective on pathways for treatment …

JR Bishop, L Zhang, P Lizano - Harvard review of psychiatry, 2022 - journals.lww.com
Dysregulation of immunological and inflammatory processes is frequently observed in
psychotic disorders. Numerous studies have examined the complex components of innate …

Interventions for prodromal stage of psychosis

DB Kuharic, I Kekin, J Hew… - Cochrane Database …, 2019 - cochranelibrary.com
Background Psychosis is a serious mental condition characterised by a loss of contact with
reality. There may be a prodromal period or stage of psychosis, where early signs of …

Right care, first time: a highly personalised and measurement‐based care model to manage youth mental health

IB Hickie, EM Scott, SP Cross, F Iorfino… - Medical Journal of …, 2019 - Wiley Online Library
Mood and psychotic syndromes most often emerge during adolescence and young
adulthood, a period characterised by major physical and social change. Consequently, the …

[HTML][HTML] Immune and oxidative stress biomarkers in pediatric psychosis and psychosis-risk: Meta-analyses and systematic review

JH Taylor, J Bermudez-Gomez, M Zhou… - Brain, Behavior, and …, 2024 - Elsevier
Objective While genetic and cohort studies suggest immune and reduction/oxidation (redox)
alterations occur in psychosis, less is known about potential alterations in children and …

Association of baseline inflammatory markers and the development of negative symptoms in individuals at clinical high risk for psychosis

DR Goldsmith, E Haroon, AH Miller, J Addington… - Brain, behavior, and …, 2019 - Elsevier
Negative symptoms are common in individuals at clinical high-risk (CHR) for psychosis and
are associated with worse functional outcomes. Inflammation may be one mechanism …

Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at …

SR Susai, C Healy, D Mongan, M Heurich… - Translational …, 2022 - nature.com
Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids
(PUFAs) in early psychosis. The present study investigates the molecular mechanism of …

Inflammatory biomarkers in individuals at clinical high risk for psychosis (CHR-P): State or trait?

R Khoury, HA Nasrallah - Schizophrenia research, 2018 - Elsevier
Background Studies linking neuro-inflammation to psychotic episodes has been rapidly
expanding. Assessments of changes in inflammatory biomarkers in prodromal patients who …

[HTML][HTML] Effects of marine-derived n–3 PUFA supplementation on soluble adhesion molecules: A systematic review and dose-response meta-analysis of randomized …

M Shirani, S Talebi, O Sadeghi, S Hassanizadeh… - Pharmacological …, 2023 - Elsevier
Long-chain n–3 poly unsaturated fatty acids have anti-inflammatory effects but their effects
on serum levels of adhesion molecules are inconsistent and contradictory. In this updated …

The efficacy of nutritional supplements for the adjunctive treatment of schizophrenia in adults: a systematic review and network meta-analysis

X Xu, G Shao, X Zhang, Y Hu, J Huang, Y Su… - Psychiatry …, 2022 - Elsevier
Nutritional supplementations have been widely used as adjunctive treatments for
schizophrenia. However, among these supplementations, of which the most beneficial is …

Shared biological pathways between antipsychotics and omega-3 fatty acids: a key feature for schizophrenia preventive treatment?

A Frajerman, L Scoriels, O Kebir… - International Journal of …, 2021 - mdpi.com
Schizophrenia typically emerges during adolescence, with progression from an ultra-high
risk state (UHR) to the first episode of psychosis (FEP) followed by a chronic phase. The …