Gut barrier disruption and chronic disease
The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
Gut bacteria and neurotransmitters
LMT Dicks - Microorganisms, 2022 - mdpi.com
Gut bacteria play an important role in the digestion of food, immune activation, and
regulation of entero-endocrine signaling pathways, but also communicate with the central …
regulation of entero-endocrine signaling pathways, but also communicate with the central …
Systemic inflammation after stroke: implications for post‐stroke comorbidities
Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …
research, and the modulation of neuroinflammatory pathways has been identified as a …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Immune responses to stroke: mechanisms, modulation, and therapeutic potential
C Iadecola, MS Buckwalter… - The Journal of clinical …, 2020 - Am Soc Clin Investig
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Gut microbiota–derived short-chain fatty acids promote poststroke recovery in aged mice
J Lee, J d'Aigle, L Atadja, V Quaicoe… - Circulation …, 2020 - Am Heart Assoc
Rationale: The elderly experience profound systemic responses after stroke, which
contribute to higher mortality and more severe long-term disability. Recent studies have …
contribute to higher mortality and more severe long-term disability. Recent studies have …
Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy
Oncogenesis is associated with intestinal dysbiosis, and stool shotgun metagenomic
sequencing in individuals with this condition might constitute a non-invasive approach for …
sequencing in individuals with this condition might constitute a non-invasive approach for …
Rapid gut dysbiosis induced by stroke exacerbates brain infarction in turn
K Xu, X Gao, G Xia, M Chen, N Zeng, S Wang, C You… - Gut, 2021 - gut.bmj.com
Objective Stroke is a leading cause of death and disability worldwide. Neuroprotective
approaches have failed in clinical trials, thus warranting therapeutic innovations with …
approaches have failed in clinical trials, thus warranting therapeutic innovations with …
Translocation of a gut pathobiont drives autoimmunity in mice and humans
Despite multiple associations between the microbiota and immune diseases, their role in
autoimmunity is poorly understood. We found that translocation of a gut pathobiont …
autoimmunity is poorly understood. We found that translocation of a gut pathobiont …
Gut microbiota and their metabolites in stroke: a double-edged sword
Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …
gastrointestinal system. A growing body of evidence supports the role of the gut and its …