[HTML][HTML] IgG/IgM antiphospholipid antibodies present in the classification criteria for the antiphospholipid syndrome: a critical review of their association with …

H Kelchtermans, L Pelkmans, B De Laat… - Journal of thrombosis …, 2016 - Elsevier
Essentials• The clinical value of IgM antibodies in thrombotic antiphospholipid syndrome
(APS) is debated.• By review of literature, we reconsidered the clinical value of IgM …

Delineating the deranged immune system in the antiphospholipid syndrome

LL van den Hoogen, JAG van Roon… - Autoimmunity …, 2016 - Elsevier
The antiphospholipid syndrome (APS) is a systemic autoimmune disease that is
characterized serologically by the presence of antiphospholipid antibodies (aPL) and …

[HTML][HTML] New biomarkers for atherothrombosis in antiphospholipid syndrome: genomics and epigenetics approaches

C Lopez-Pedrera, N Barbarroja… - Frontiers in …, 2019 - frontiersin.org
Antiphospholipid Syndrome (APS) is an autoimmune disorder, characterized by pregnancy
morbidity and/or a hyper coagulable state involving the venous or the arterial vasculature …

Genetic risk factors in thrombotic primary antiphospholipid syndrome: A systematic review with bioinformatic analyses

MA Islam, SS Khandker, F Alam, MA Kamal… - Autoimmunity Reviews, 2018 - Elsevier
Abstract Background Antiphospholipid Syndrome (APS) is an autoimmune multifactorial
disorder. Genetics is believed to play a contributory role in the pathogenesis of APS …

Genetics of antiphospholipid syndrome

L Ortiz-Fernández, AH Sawalha - Current Rheumatology Reports, 2019 - Springer
Abstract Purpose of Review Antiphospholipid syndrome (APS) is a rare heterogenous
disorder associated with the presence of antiphospholipid antibodies and can present in a …

Idiopathic sudden sensorineural hearing loss: classic cardiovascular and new genetic risk factors

F Ballesteros, D Tassies, JC Reverter, I Alobid… - Audiology and …, 2012 - karger.com
Background: The main causative process in idiopathic sudden sensorineural hearing loss
(iSSNHL) has yet to be explained or demonstrated. The clinical picture supports vascular …

Platelets in rheumatic diseases: friend or foe?

A Yuri Gasparyan, L Ayvazyan… - Current …, 2014 - ingentaconnect.com
Platelets are intimately involved in hemostasis, inflammation, innate and adaptive immunity,
tissue regeneration and other physiological and pathological processes. Their granular …

[HTML][HTML] Genetic factors in antiphospholipid syndrome: preliminary experience with whole exome sequencing

A Barinotti, M Radin, I Cecchi, SG Foddai… - International journal of …, 2020 - mdpi.com
As in many autoimmune diseases, the pathogenesis of the antiphospholipid syndrome
(APS) is the result of a complex interplay between predisposing genes and triggering …

An immunogenomic exome landscape of triple positive primary antiphospholipid patients

A Guffroy, L Jacquel, Y Seeleuthner, N Paul… - Genes & …, 2024 - nature.com
Primary antiphospholipid syndrome is characterized by thrombosis and autoantibodies
directed against phospholipids or associated proteins. The genetic etiology of PAPS …

Antiphospholipid antibody-mediated thrombotic mechanisms in antiphospholipid syndrome: towards pathophysiology-based treatment

A Islam, F Alam, T Haryo Sasongko… - Current …, 2016 - ingentaconnect.com
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by a
persistently high titer of antiphospholipid antibodies (aPLs). In addition to pregnancy …