Quinolines and isoquinolines as HIV-1 inhibitors: Chemical structures, action targets, and biological activities
S Hu, J Chen, JX Cao, SS Zhang, SX Gu, FE Chen - Bioorganic Chemistry, 2023 - Elsevier
Human immunodeficiency virus type 1 (HIV-1), a lentivirus that causes acquired
immunodeficiency syndrome (AIDS), poses a serious threat to global public health. Since …
immunodeficiency syndrome (AIDS), poses a serious threat to global public health. Since …
Improving the anti-HIV-1 activity and solubility of poorly water-soluble DAPYs by heteroaromatic replacement strategy: From naphthalene-DAPYs to quinoline-DAPYs
RL Zhou, C Yu, C Pannecouque, E De Clercq… - Bioorganic …, 2023 - Elsevier
To enhance the anti-HIV-1 efficacy and solubility of our previously documented NNRTI 1, a
collection of innovative quinoline-substituted DAPY derivatives were devised using …
collection of innovative quinoline-substituted DAPY derivatives were devised using …