Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …

The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

A substantial and increasing number of human diseases are associated with changes in the
gut microbiota, and discovering the molecules and mechanisms underlying these …

Abstract Group A Streptococcus (GAS; Streptococcus pyogenes) is a bacterial pathogen for
which a commercial vaccine for humans is not available. Employing the advantages of high …

The composition of the Gram-positive cell wall is typically described as containing
peptidoglycan, proteins and essential secondary cell wall structures called teichoic acids …

Cell surface carbohydrates have been proven optimal targets for vaccine development.
Conjugation of polysaccharides to a carrier protein triggers a T-cell-dependent immune …

The surface of cells is coated with a dense layer of glycans, known as the cell glycocalyx.
The complex glycans in the glycocalyx are involved in various biological events, such as …

Streptococcus pyogenes is an important global pathogen, causing considerable morbidity
and mortality, especially in low and middle income countries where rheumatic heart disease …

Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is a Gram-positive
human-exclusive pathogen, responsible for more than 500 000 deaths annually worldwide …

Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human
infection with invasive disease incidence and clinical manifestations comparable to the …