The class B2 of GPCRs known as adhesion G protein-coupled receptors (aGPCRs) has
come under increasing academic and nonacademic research focus over the past decade …

The assembly and specification of synapses in the brain is incompletely understood,–.
Latrophilin-3 (encoded by Adgrl3, also known as Lphn3)—a postsynaptic adhesion G …

Abstract Adhesion G Protein-Coupled Receptors (aGPCRs) are key cell-adhesion
molecules involved in numerous physiological functions. aGPCRs have large multi-domain …

Combinatorial networks of cell adhesion molecules and cell surface receptors drive
fundamental aspects of neural circuit establishment and function. However, the intracellular …

Planar cell polarity (PCP), essential to multicellular developmental processes, arises when
cells polarize and align across tissues. Central to PCP is CELSR1, an atypical cadherin …

The extracellular matrix (ECM) is a network of macromolecules that presents a vital scaffold
for cells and enables multiple ways of cellular communication. Thus, it is essential for many …

Abstract Cadherin EGF Laminin G seven-pass G-type receptors (CELSRs or ADGRCs) are
conserved adhesion G protein-coupled receptors which are essential for animal …

In the developing brain, groups of neurons organize into functional circuits that direct diverse
behaviors. One such behavior is the evolutionarily conserved acoustic startle response …

Adhesion G protein-coupled receptor (aGPCR) signaling influences development and
homeostasis in a wide range of tissues. In the current model for aGPCR signaling, ligand …

The growth and survival of cells with different fitness, such as those with a proliferative
advantage or a deleterious mutation, is controlled through cell competition. During …