It has been hypothesized that one mechanism through which physical activity provides
benefits to cognition and mood is via increasing brain‐derived neurotrophic factor (BDNF) …

Within the past decade, multiple lines of evidence have converged to identify a critical role
for activity-regulated myelination in tuning the function of neural networks. In this Review, we …

Background The mechanisms through which physical activity supports healthy brain function
remain to be elucidated. One hypothesis suggests that increased brain-derived neurotrophic …

Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …

Multiple sclerosis (MS) is a chronic, inflammatory, and degenerative disease of the central
nervous system (CNS). Inflammation is observed in all stages of MS, both within and around …

The growing incidence of neurodegenerative disorders in our populations is leading the
research to identify potential biomarkers and targets for facilitating their early management …

Background Multiple sclerosis is an autoimmune demyelinating disease marked by the
involvement of multiple pathophysiological pathways, including BDNF. BDNF (brain-derived …

Background: Mental disorders is one of the main causes of disability and lower life
expectancy among patients with Multiple Sclerosis (MS). The present trial aimed to examine …

Background and purpose Brain derived neurotrophic factor (BDNF) is suggested to play a
neuroprotective role in multiple sclerosis (MS). However, the BDNF response to long‐term …

Previous work in culture has shown that basal forebrain (BF) oligodendrocyte (OLG) lineage
cells respond to BDNF by increasing DNA synthesis and differentiation. Further, in the BF in …