From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I

M Naghavi, P Libby, E Falk, SW Casscells, S Litovsky… - Circulation, 2003 - Am Heart Assoc
Atherosclerotic cardiovascular disease results in> 19 million deaths annually, and coronary
heart disease accounts for the majority of this toll. Despite major advances in treatment of …

PET imaging of inflammation in atherosclerosis

JM Tarkin, FR Joshi, JHF Rudd - Nature Reviews Cardiology, 2014 - nature.com
PET imaging of atherosclerosis can quantify several in vivo pathological processes
occurring within the arterial system. 18F-fluorodeoxyglucose (FDG) is the most-commonly …

Imaging Atherosclerotic Plaque Inflammation With [18F]-Fluorodeoxyglucose Positron Emission Tomography

JHF Rudd, EA Warburton, TD Fryer, HA Jones… - Circulation, 2002 - Am Heart Assoc
Background—Atherosclerotic plaque rupture is usually a consequence of inflammatory cell
activity within the plaque. Current imaging techniques provide anatomic data but no …

In Vivo 18F-Fluorodeoxyglucose Positron Emission Tomography Imaging Provides a Noninvasive Measure of Carotid Plaque Inflammation in Patients

A Tawakol, RQ Migrino, GG Bashian, S Bedri… - Journal of the American …, 2006 - jacc.org
Objectives: Given the importance of inflammation in atherosclerosis, we sought to determine
if atherosclerotic plaque inflammation could be measured noninvasively in humans using …

Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography

N Tahara, H Kai, M Ishibashi, H Nakaura… - Journal of the American …, 2006 - jacc.org
Objectives: We investigated whether simvastatin attenuates plaque inflammation by using
18F-fluorodeoxyglucose positron emission tomography (18FDG-PET) co-registered with …

Hypoxia But Not Inflammation Augments Glucose Uptake in Human Macrophages: Implications for Imaging Atherosclerosis With 18Fluorine-Labeled 2-Deoxy-D …

EJ Folco, Y Sheikine, VZ Rocha, T Christen… - Journal of the American …, 2011 - jacc.org
Objectives: This study investigated the regulation of glucose uptake in cells that participate
in atherogenesis by stimuli relevant to this process, to gain mechanistic insight into the origin …

Role of inflammation in atherosclerosis

LG Spagnoli, E Bonanno, G Sangiorgi… - Journal of nuclear …, 2007 - Soc Nuclear Med
Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are
characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques …

Feasibility of FDG imaging of the coronary arteries: comparison between acute coronary syndrome and stable angina

IS Rogers, K Nasir, AL Figueroa, RC Cury… - JACC: Cardiovascular …, 2010 - jacc.org
Objectives: This study tested the hypothesis that fluorodeoxyglucose (FDG) uptake within the
ascending aorta and left main coronary artery (LM), measured using positron emission …

[HTML][HTML] Vessel wall imaging of the intracranial and cervical carotid arteries

YJ Choi, SC Jung, DH Lee - Journal of stroke, 2015 - ncbi.nlm.nih.gov
Vessel wall imaging can depict the morphologies of atherosclerotic plaques, arterial walls,
and surrounding structures in the intracranial and cervical carotid arteries beyond the simple …

18F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study

M Ogawa, S Ishino, T Mukai, D Asano… - Journal of Nuclear …, 2004 - Soc Nuclear Med
The rupture of atherosclerotic plaques and the subsequent formation of thrombi are the main
factors responsible for myocardial and cerebral infarctions. Thus, the detection of vulnerable …