Behavioral assessment of sensory, motor, emotion, and cognition in rodent models of intracerebral hemorrhage
X Shi, H Bai, J Wang, J Wang, L Huang, M He… - Frontiers in …, 2021 - frontiersin.org
Intracerebral hemorrhage (ICH) is the second most common type of stroke and has one of
the highest fatality rates of any disease. There are many clinical signs and symptoms after …
the highest fatality rates of any disease. There are many clinical signs and symptoms after …
Molecular mechanisms of cognitive dysfunction following traumatic brain injury
KR Walker, G Tesco - Frontiers in aging neuroscience, 2013 - frontiersin.org
Traumatic brain injury (TBI) results in significant disability due to cognitive deficits
particularly in attention, learning and memory, and higher-order executive functions. The …
particularly in attention, learning and memory, and higher-order executive functions. The …
Applications of the Morris water maze in translational traumatic brain injury research
Acquired traumatic brain injury (TBI) is frequently accompanied by persistent cognitive
symptoms, including executive function disruptions and memory deficits. The Morris Water …
symptoms, including executive function disruptions and memory deficits. The Morris Water …
General Anesthetics Inhibit LPS-Induced IL-1β Expression in Glial Cells
T Tanaka, S Kai, T Matsuyama, T Adachi, K Fukuda… - PloS one, 2013 - journals.plos.org
Background Glial cells, including microglia and astrocytes, are considered the primary
source of proinflammatory cytokines in the brain. Immune insults stimulate glial cells to …
source of proinflammatory cytokines in the brain. Immune insults stimulate glial cells to …
Tumor necrosis factor alpha antagonism improves neurological recovery in murine intracerebral hemorrhage
B Lei, HN Dawson, B Roulhac-Wilson, H Wang… - Journal of …, 2013 - Springer
Background Intracerebral hemorrhage (ICH) is a devastating stroke subtype characterized
by a prominent neuroinflammatory response. Antagonism of pro-inflammatory cytokines by …
by a prominent neuroinflammatory response. Antagonism of pro-inflammatory cytokines by …
Neuroimaging of subacute brain inflammation and microstructural changes predicts long-term functional outcome after experimental traumatic brain injury
S Missault, C Anckaerts, I Blockx, S Deleye… - Journal of …, 2019 - liebertpub.com
There is currently a lack of prognostic biomarkers to predict the different sequelae following
traumatic brain injury (TBI). The present study investigated the hypothesis that subacute …
traumatic brain injury (TBI). The present study investigated the hypothesis that subacute …
Predictors of late neurological deterioration after spontaneous intracerebral hemorrhage
W Sun, W Pan, PG Kranz, CE Hailey, RA Williamson… - Neurocritical care, 2013 - Springer
Background Although intracerebral hemorrhage (ICH) is a common form of cerebrovascular
disease, little is known about factors leading to neurological deterioration occurring beyond …
disease, little is known about factors leading to neurological deterioration occurring beyond …
Attenuation of traumatic brain injury-induced cognitive impairment in mice by targeting increased cytokine levels with a small molecule experimental therapeutic
Background Evidence from clinical studies and preclinical animal models suggests that
proinflammatory cytokine overproduction is a potential driving force for pathology …
proinflammatory cytokine overproduction is a potential driving force for pathology …
MW151 inhibited IL-1β levels after traumatic brain injury with no effect on microglia physiological responses
AD Bachstetter, Z Zhou, RK Rowe, B Xing… - PLoS …, 2016 - journals.plos.org
A prevailing neuroinflammation hypothesis is that increased production of proinflammatory
cytokines contributes to progressive neuropathology, secondary to the primary damage …
cytokines contributes to progressive neuropathology, secondary to the primary damage …
Ergosta-7, 9 (11), 22-trien-3β-ol alleviates intracerebral hemorrhage-induced brain injury and bv-2 microglial activation
PJ Hsueh, MH Wang, CJ Hsiao, CK Chen, FL Lin… - Molecules, 2021 - mdpi.com
Intracerebral hemorrhage (ICH) is a devastating neurological disorder characterized by an
exacerbation of neuroinflammation and neuronal injury, for which few effective therapies are …
exacerbation of neuroinflammation and neuronal injury, for which few effective therapies are …