The widespread use of antibiotics in the past 80 years has saved millions of human lives,
facilitated technological progress and killed incalculable numbers of microbes, both …

Antibiotic resistance is one of the greatest challenges of the twenty-first century. However,
the increasing understanding of bacterial pathogenesis and intercellular communication has …

Surface plasmon resonance (SPR)-based optical biosensors offer real-time and label-free
analysis of protein interactions, which has extensively contributed to the discovery and …

Anthrax is a highly lethal infectious disease caused by the spore-forming bacterium Bacillus
anthracis. It not only causes natural infection in humans but also poses a great threat as an …

Today's medicine has to deal with the emergence of multi-drug resistant bacteria, and is
beginning to be confronted with pan-resistant microbes. This worsening inadequacy of the …

We developed a europium nanoparticle-based immunoassay (ENIA) for the sensitive
detection of anthrax protective antigen (PA). The ENIA exhibited a linear dose-dependent …

The emergence and global spread of the SARS-CoV-2 Omicron variants, which carry an
unprecedented number of mutations, raise serious concerns due to the reduced efficacy of …

Many techniques rely on the binding activity of surface-immobilized proteins, including
antibody-based affinity biosensors for the detection of analytes, immunoassays, protein …

Antibody therapy remains the only effective treatment for toxin-mediated diseases. The
development of hybridoma technology has allowed the isolation of monoclonal antibodies …

Passive immunoprophylaxis or immunotherapy with norovirus-neutralizing monoclonal
antibodies (MAbs) could be a useful treatment for high-risk populations, including infants …