Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

S Bindu, S Mazumder, U Bandyopadhyay - Biochemical pharmacology, 2020 - Elsevier
Owing to the efficacy in reducing pain and inflammation, non-steroidal anti-inflammatory
drugs (NSAIDs) are amongst the most popularly used medicines confirming their position in …

Non-steroidal anti-inflammatory drugs (NSAIDs): A current insight into its molecular mechanism eliciting organ toxicities

NK Panchal, EP Sabina - Food and Chemical Toxicology, 2023 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of medications that are routinely
been used across the world. Their analgesic, anti-inflammatory, and antipyretic effects have …

Redox signaling in the gastrointestinal tract

S Pérez, R Taléns-Visconti, S Rius-Pérez… - Free Radical Biology …, 2017 - Elsevier
Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

[HTML][HTML] Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection

X He, X Wang, L Yang, Z Yang, W Yu, Y Wang… - … Pharmaceutica Sinica B, 2022 - Elsevier
The treatment of Alzheimer's disease (AD) is one of the most difficult challenges in
neurodegenerative diseases due to the insufficient blood‒brain barrier (BBB) permeability …

Cinnamon aqueous extract attenuates diclofenac sodium and oxytetracycline mediated hepato-renal toxicity and modulates oxidative stress, cell apoptosis, and …

GE Elshopakey, ST Elazab - Veterinary Sciences, 2021 - mdpi.com
Among commonly consumed anti-inflammatory and antimicrobial drugs are diclofenac
sodium (DFS) and oxytetracycline (OTC), especially in developing countries because they …

Taurine protects cisplatin induced cardiotoxicity by modulating inflammatory and endoplasmic reticulum stress responses

S Chowdhury, K Sinha, S Banerjee, PC Sil - Biofactors, 2016 - Wiley Online Library
Oxidative stress, ER stress, inflammation, and apoptosis results in the pathogenesis of
cisplatin‐induced cardiotoxicity. The present study was designed to investigate the signaling …

Morin protects gastric mucosa from nonsteroidal anti-inflammatory drug, indomethacin induced inflammatory damage and apoptosis by modulating NF-κB pathway

K Sinha, P Sadhukhan, S Saha, PB Pal… - Biochimica et Biophysica …, 2015 - Elsevier
Background Deregulation in prostaglandin (PG) biosynthesis, severe oxidative stress,
inflammation and apoptosis contribute to the pathogenesis of nonsteroidal anti-inflammatory …

Polysaccharide isolated from Chinese jujube fruit (Zizyphus jujuba cv. Junzao) exerts anti-inflammatory effects through MAPK signaling

R Zhan, L Xia, J Shao, C Wang, D Chen - Journal of Functional Foods, 2018 - Elsevier
A peptic polysaccharide (ZJP) was isolated from Zizyphus jujuba cv. Junzao by hot water
extraction and chromatographic purification. Structural characterization showes that ZJP has …

Targeting MAPKs, NF‐κB, and PI3K/AKT pathways by methyl palmitate ameliorates ethanol‐induced gastric mucosal injury in rats

HH Arab, SA Salama, AH Eid… - Journal of cellular …, 2019 - Wiley Online Library
Excessive drinking of alcohol has been frequently associated with gastric injury; however, its
underlying molecular mechanisms have been inadequately investigated. Methyl palmitate …

Coumarins of Ferulopsis hystrix: LC–MS Profiling and Gastroprotective and Antioxidant Activities of Skimmin and Peucenidin

YG Razuvaeva, AA Toropova, SM Salchak… - Applied Sciences, 2023 - mdpi.com
Ferulopsis hystrix is a perennial plant of the Apiaceae family. In Buryat and Mongolian
medicine, it is used as a substitute for Costus speciosus roots (ru rta), and in Tibetan …