Thermoresponsive polymers hold great potential in the biomedical field, since they enable
the fabrication of cell sheets, in situ drug delivery and 3D-printing under physiological …

The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

A concentrated fish soup could be gelled in the winter and re-solled upon heating. In
contrast, some synthetic copolymers exhibit an inverse sol–gel transition with spontaneous …

Environmentally responsive hydrogels have the ability to turn from solution to gel when a
specific stimulus is applied. Thermoresponsive hydrogels utilize temperature change as the …

Multifunctional theranostic nanoplatforms (NPs) in response to environment stimulations for
on-demand drug release are highly desirable. Herein, the near-infrared (NIR)-absorbing …

With the rapid progress of biomedical technology, hydrogels that can be prepared under bio-
friendly conditions are urgently needed. In situ gelling systems have been extensively …

Aqueous solutions that undergo sol-to-gel transition as the temperature increases have
been extensively studied during the last decade. The material can be designed by …

In the area of parenteral controlled release formulations, in situ forming implants (ISFI) are
attractive alternatives to preformed implants and microparticles. ISFI avoid the use of large …

Stimuli-sensitive block copolymer hydrogels, which are reversible polymer networks formed
by physical interactions and exhibit a sol–gel phase-transition in response to external …

The low solubility in biological fluids displayed by about 50% of the drugs still remains the
main limitation in oral, parenteral, and transdermal administration. Among the existing …