As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Bone metastases are devastating complications of cancer. They are particularly common in
prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy …

Abstract Space flight factors (SFF) significantly affect the operating activity of astronauts
during deep space missions. Gravitational overloads, hypo-magnetic field and ionizing …

Increased fracture risk is commonly reported in cancer patients receiving radiotherapy,
particularly at sites within the field of treatment. The direct and systemic effects of ionizing …

Accidental radiation exposure is a threat to human health that necessitates effective clinical
planning and diagnosis. Minimally invasive biomarkers that can predict long-term radiation …

Acute radiation sickness (ARS) following exposure to ionizing irradiation is characterized by
radiation-induced multiorgan dysfunction/failure that refers to progressive dysfunction of two …

Radioprotective agents have been developed to protect patients against the damaging and
lethal effects of ionizing radiation. However, in addition to the intrinsic ability to target …

Aim To determine the efficacy of human relaxin‐2 (hRLX2) in reversing radiation‐induced
bladder fibrosis and lower urinary tract dysfunction (LUTD). Radiation cystitis is a …

Prospective severity assessment is legally required in many countries to ensure high-quality
research along with high welfare standards for laboratory animals. Mice and rats, the most …

Purpose Severity scoring systems for ionizing radiation-induced gastrointestinal injury have
been used in animal radiation models, human studies involving the use of radiation therapy …