[HTML][HTML] Revisiting metallodrugs for the treatment of skin cancers
CM Manzano, DH Nakahata, REF de Paiva - Coordination Chemistry …, 2022 - Elsevier
Metallodrugs were classically screened against skin cancer (either in vitro or in vivo) at the
peak of the development of platinum anticancer agents. New systematic studies appeared in …
peak of the development of platinum anticancer agents. New systematic studies appeared in …
Recent Advances for Chiral Sulfoxides in Asymmetric Catalysis
MM Yang, S Wang, ZB Dong - Synthesis, 2022 - thieme-connect.com
Chiral sulfoxide is considered to be an ideal candidate ligand for transition-metal-catalyzed
asymmetric reactions due to its ease of synthesis, stability, and exceptional S-stereological …
asymmetric reactions due to its ease of synthesis, stability, and exceptional S-stereological …
Potent half-sandwich iridium (III) and ruthenium (II) anticancer complexes containing a P^ O-chelated ligand
Q Du, L Guo, M Tian, X Ge, Y Yang, X Jian, Z Xu… - …, 2018 - ACS Publications
We herein report the synthesis, characterization, and anticancer activity of a series of iridium
(III) and ruthenium (II) half-sandwich complexes of the type [(Cpx/arene) M (P^ O) Cl] PF6 …
(III) and ruthenium (II) half-sandwich complexes of the type [(Cpx/arene) M (P^ O) Cl] PF6 …
Synthesis of NNN chiral ruthenium complexes and their cytotoxicity studies
The synthesis and characterization of chiral pincer-ruthenium complexes of the type
(R2NNN) RuCl2 (PPh3)(R= 3-methylbutyl and 3, 3-dimethylbutyl) is reported here. The …
(R2NNN) RuCl2 (PPh3)(R= 3-methylbutyl and 3, 3-dimethylbutyl) is reported here. The …
Ph-responsive release of ruthenium metallotherapeutics from mesoporous silica-based nanocarriers
Ruthenium complexes are attracting interest in cancer treatment due to their potent cytotoxic
activity. However, as their high toxicity may also affect healthy tissues, efficient and selective …
activity. However, as their high toxicity may also affect healthy tissues, efficient and selective …
(Pentamethylcyclopentadienyl)chloridoiridium(III) Complex Bearing Bidentate Ph2PCH2CH2SPh-κP,κS Ligand
G Ludwig, I Ranđelović, D Dimić, T Komazec… - Biomolecules, 2024 - mdpi.com
The (pentamethylcyclopentadienyl) chloridoiridium (III) complex bearing a κ P, κ S-bonded
Ph2PCH2CH2SPh ligand ([Ir (η5-C5Me5) Cl (Ph2P (CH2) 2SPh-κ P, κ S)] PF6,(1)] was …
Ph2PCH2CH2SPh ligand ([Ir (η5-C5Me5) Cl (Ph2P (CH2) 2SPh-κ P, κ S)] PF6,(1)] was …
Ruthenium (II) complexes bearing benzimidazole-based N-heterocyclic carbene (NHC) ligands as potential antimicrobial, antioxidant, enzyme inhibition, and …
L Boubakri, A Chakchouk-Mtiba, O Naouali… - Journal of …, 2022 - Taylor & Francis
In this work, new substituted benzimidazolium salts 2a–d having different groups on the side
chain have been synthesized and reacted with Ag2O to produce Ag (I) N-heterocyclic …
chain have been synthesized and reacted with Ag2O to produce Ag (I) N-heterocyclic …
The fluorine effect in zwitterionic half-sandwich iridium (III) anticancer complexes
Y Yang, L Guo, X Ge, T Zhu, W Chen, H Zhou… - Inorganic …, 2019 - ACS Publications
The rational design by the introduction of fluorine into a compound has achieved success in
the development of organic anticancer drugs. However, the fluorine effect in metal-based …
the development of organic anticancer drugs. However, the fluorine effect in metal-based …
Synthesis and biological evaluation of zwitterionic half-sandwich Rhodium (III) and Ruthenium (II) organometallic complexes
L Guo, X Hu, Y Yang, W An, J Gao, Q Liu, Z Liu - Bioorganic Chemistry, 2021 - Elsevier
Herein we present the synthesis and characterization of a panel of structurally related
zwitterionic piano-stool rhodium (III) and ruthenium (II) complexes. The identities of these …
zwitterionic piano-stool rhodium (III) and ruthenium (II) complexes. The identities of these …
Aminophosphine ligands as a privileged platform for development of antitumoral ruthenium (ii) arene complexes
LM Broomfield, C Alonso-Moreno, E Martin… - Dalton …, 2017 - pubs.rsc.org
The rapid and modular synthesis of the aminophosphine core has been exploited as a tool
for rapid development of antitumoral metallodrug candidates. Starting with a series of …
for rapid development of antitumoral metallodrug candidates. Starting with a series of …