Motivation Chromosomal patterning of gene expression in cancer can arise from
aneuploidy, genome disorganization or abnormal DNA methylation. To map such patterns …

This article presents a selective survey of algorithms for the offline detection of multiple
change points in multivariate time series. A general yet structuring methodological strategy …

Abstract Analysis of large gene expression datasets from biopsies of cancer patients can
identify co-expression signatures representing particular biomolecular events in cancer …

In this paper, we propose a novel approach for the optimal identification of correlated
segments in noisy correlation matrices. The proposed model is known as CoSeNet …

In many cancers, mechanisms of gene regulation can be severely altered. Identification of
deregulated genes, which do not follow the regulation processes that exist between …

Ce travail s' intéresse au problème de détection de ruptures multiples dans des signaux
physiologiques (univariés ou multivariés). Ce type de signaux comprend par exemple les …

In computational biology, numerous recent studies have been dedicated to the analysis of
the chromatin structure within the cell by two‐dimensional segmentation methods. Motivated …

We propose a methodology for the identification of transcription factors involved in the
deregulation of genes in tumoral cells. This strategy is based on the inference of a reference …

Molecular activities in chromosomal regions can be shaped by diverse biological processes,
including genome structural alteration, genome reorganization, and epigenetic …