Immunoglobulin A (IgA) plays a key role in defending mucosal surfaces against attack by
infectious microorganisms. Such sites present a major site of susceptibility due to their vast …

Immunoglobulin A (IgA) is the most abundant antibody class present at mucosal surfaces.
The production of IgA exceeds the production of all other antibodies combined, supporting …

Immunoglobulin A (IgA) is the most abundant immunoglobulin synthesized in the human
body. It has the highest concentration in the mucosa and is second only to IgG in serum. IgA …

The prevailing concept regarding the immunological function of immunoglobulin A (IgA) is
that it binds to and neutralizes pathogens to prevent infection at mucosal sites of the body …

Over the last decades, cancer immunotherapies such as checkpoint blockade and adoptive
T cell transfer have been a game changer in many aspects and have improved the treatment …

Immunoglobulin E (IgE) antibodies are well known for their role in mediating allergic
reactions, and their powerful effector functions activated through binding to Fc receptors …

Antibody therapy of cancer is increasingly used in the clinic and has improved patient's life
expectancy. Except for immune checkpoint inhibition, the mode of action of many antibodies …

Human papillomavirus (HPV) infection is a causative factor for various cancers of the
anogenital region and oropharynx, and is supposed to play an important cofactor role for …

Therapeutic monoclonal antibodies (mAb), directed toward either tumor antigens or
inhibitory checkpoints on immune cells, are effective in cancer therapy. Increasing evidence …

Antibody-dependent cellular phagocytosis (ADCP) by macrophages, an important effector
function of tumor targeting antibodies, is hampered by 'Don´ t Eat Me!'signals such as CD47 …