Immune cells in the BBB disruption after acute ischemic stroke: targets for immune therapy?

Y Qiu, C Zhang, A Chen, H Wang, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

No-reflow post-recanalization in acute ischemic stroke: mechanisms, measurements, and molecular markers

CP Sperring, WM Savage, MG Argenziano, VP Leifer… - Stroke, 2023 - Am Heart Assoc
Acute ischemic stroke remains the primary cause of disability worldwide. For patients with
large vessel occlusions, intravenous thrombolysis followed by mechanical thrombectomy …

Neutrophil–lymphocyte ratio in acute ischemic stroke: Immunopathology, management, and prognosis

D Sharma, KJ Spring… - Acta Neurologica …, 2021 - Wiley Online Library
There is an ongoing need for accurate prognostic biomarkers in the milieu of acute ischemic
stroke (AIS) receiving reperfusion therapy. Neutrophil–lymphocyte ratio (NLR) has been …

Stroke and emerging blood biomarkers: a clinical prospective

A Gkantzios, D Tsiptsios, S Karatzetzou… - Neurology …, 2022 - mdpi.com
Stroke constitutes the primary source of adult functional disability, exhibiting a paramount
socioeconomic burden. Thus, it is of great importance that the prediction of stroke outcome …

Postoperative neutrophil-lymphocyte ratio predicts unfavorable outcome of acute ischemic stroke patients who achieve complete reperfusion after thrombectomy

Y Feng, X Bai, W Li, W Cao, X Xu, F Yu, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Purpose Only approximately half of anterior circulation large vessel occlusion (LVO) patients
receiving endovascular treatment (EVT) have a favorable outcome. The aim of this study …

Role of neutrophil-lymphocyte ratio in the prognosis of acute ischaemic stroke after reperfusion therapy: A systematic review and meta-analysis

D Sharma, KJ Spring… - Journal of Central …, 2022 - journals.sagepub.com
Background Inflammation may mediate response to acute reperfusion therapy (RT) in acute
cerebral ischaemia. Neutrophil-lymphocyte ratio (NLR), an inflammatory biomarker, may …

Elevated serum uric acid increases the risk of ischemic stroke recurrence and its inflammatory mechanism in older adults

HY Zhu, SZ Zhao, ML Zhang, Y Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Background Serum uric acid (UA) has been reported to be associated with ischemic stroke
and inflammation. However, whether or not UA is related to the recurrence of ischemic …

Plasma lipid mediators associate with clinical outcome after successful endovascular thrombectomy in patients with acute ischemic stroke

J Hao, Y Feng, X Xu, L Li, K Yang, G Dai… - Frontiers in …, 2022 - frontiersin.org
Background Neuroinflammatory response contributes to early neurological deterioration
(END) and unfavorable long-term functional outcome in patients with acute ischemic stroke …

Neutrophil heterogeneity and its roles in the inflammatory network after ischemic stroke

M Xie, Y Hao, L Feng, T Wang, M Yao… - Current …, 2023 - benthamdirect.com
As the first peripheral immune cells to enter the brain after ischemic stroke, neutrophils are
important participants in stroke-related neuroinflammation. Neutrophils are quickly mobilized …

Increased neutrophil-to-lymphocyte ratio predicts the development of post-stroke infections in patients with acute ischemic stroke

L He, J Wang, F Wang, L Zhang, L Zhang, W Zhao - BMC neurology, 2020 - Springer
Background Infections could increase the risk of poor outcome in patients with acute
ischemic stroke (AIS). The peripheral neutrophil-to-lymphocyte ratio (NLR) is an important …