[HTML][HTML] Pediatric low-grade glioma in the era of molecular diagnostics

S Ryall, U Tabori, C Hawkins - Acta neuropathologica communications, 2020 - Springer
Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

2021 WHO classification of tumours of the central nervous system: a review for the neuroradiologist

C McNamara, K Mankad, S Thust, L Dixon… - Neuroradiology, 2022 - Springer
The fifth edition of the World Health Organization Classification of Tumours of the Central
Nervous System (WHO CNS5) published in 2021 builds on the 2016 edition and …

Management of pediatric low-grade glioma

P De Blank, P Bandopadhayay… - Current opinion in …, 2019 - journals.lww.com
Management of pediatric low-grade glioma : Current Opinion in Pediatrics Management of
pediatric low-grade glioma : Current Opinion in Pediatrics Log in or Register Subscribe to …

Treatment of pediatric low-grade gliomas

SF Sait, AM Giantini-Larsen, KR Tringale… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review Pediatric low-grade gliomas and glioneuronal tumors (pLGG)
account for approximately 30% of pediatric CNS neoplasms, encompassing a …

[HTML][HTML] The oncogenic fusion landscape in pediatric CNS neoplasms

M Roosen, Z Odé, J Bunt, M Kool - Acta Neuropathologica, 2022 - Springer
Pediatric neoplasms in the central nervous system (CNS) are the leading cause of cancer-
related deaths in children. Recent developments in molecular analyses have greatly …

[HTML][HTML] 2021 updates to the World Health Organization classification of adult-type and pediatric-type diffuse gliomas: a clinical practice review

DL Thomas - Chinese clinical oncology, 2023 - cco.amegroups.org
In 2021, the World Health Organization (WHO) Classification of Tumors of the Central
Nervous System (CNS) underwent significant restructuring to incorporate additional …

Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene …

D Stichel, D Schrimpf, B Casalini, J Meyer… - Acta …, 2019 - Springer
Molecular markers have become pivotal in brain tumor diagnostics. Mutational analyses by
targeted next-generation sequencing of DNA and array-based DNA methylation assessment …

Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors

JA Lake, AM Donson, E Prince, KD Davies… - Pediatric blood & …, 2020 - Wiley Online Library
Background The use of next‐generation sequencing for fusion identification is being
increasingly applied and aids our understanding of tumor biology. Some fusions are …

The diverse roles of RNA-binding proteins in glioma development

MX Velasco, A Kosti, LOF Penalva… - The mRNA Metabolism in …, 2019 - Springer
Post-transcriptional regulation of gene expression is fundamental for all forms of life, as it
critically contributes to the composition and quantity of a cell's proteome. These processes …

Decoding the puzzle: A multidisciplinary systematic review of adult brainstem glioma

T Ius, N Montemurro, G Lombardi, J Berardinelli… - Critical Reviews in …, 2024 - Elsevier
Adult brainstem gliomas (BSGs) are a group of rare central nervous system tumors with
varying prognoses and controversial standard treatment strategies. To provide an overview …