The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …

Rheumatoid arthritis (RA) is an autoimmune disease that commonly causes inflammation
and bone destruction in multiple joints. Inflammatory cytokines, such as IL-6 and TNF-α, play …

Rheumatoid arthritis (RA) is a multisystemic and inflammatory autoimmune disease
characterized by joint destruction. The C–C motif chemokine receptor 2 (CCR2) is mainly …

Osteoarthritis (OA) is characterized by a complex interplay of molecular signals orchestrated
by the CCL2/CCR2 axis. The pathogenesis of OA has been revealed to be influenced by a …

Osteoarthritis (OA) is a degenerative condition of the articular cartilage with chronic low-
grade inflammation. Monocytes have a fundamental role in the progression of OA, given …

Osteoclasts, macrophages and dendritic cells (DCs) can be derived from a common
trilineage myeloid progenitor of hematopoietic origin. Progenitor commitment is susceptible …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial hyperplasia
and cartilage/bone destruction with systemic comorbidities. Despite advances in …

STUDY QUESTION Does the chemokine/chemokine receptor axis, involved in immune cell
trafficking, contribute to the pathology of testicular inflammation and how does activin A …

Abstract Alzheimer's disease (AD), as a neurodegenerative disorder, distresses the elderly
in large numbers and is characterized by β-amyloid (Aβ) accumulation, elevated tau protein …

Introduction The existence of different osteoclast progenitor (OCP) subsets has been
confirmed by numerous studies. However, pathological inflammation-induced …