Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) proteins are a
diverse and evolutionarily conserved family of cytidine deaminases that provide a variety of …

The evolutionary conflict between retroviruses and their vertebrate hosts over millions of
years has led to the emergence of cellular innate immune proteins termed restriction factors …

Mutagenic processes leave distinct signatures in cancer genomes. The mutational
signatures attributed to APOBEC3 cytidine deaminases are pervasive in human cancers …

Although the APOBEC3 family of single-stranded DNA cytosine deaminases is well-known
for its antiviral factors, these enzymes are rapidly gaining attention as prominent sources of …

The interaction between human papillomaviruses (HPV) and the apolipoprotein-B mRNA-
editing catalytic polypeptide-like (APOBEC) 3 (A3) genes has garnered increasing attention …

ABSTRACT Approximately 4.4% of the human genome is comprised of endogenous
retroviral sequences, a record of an evolutionary battle between man and retroviruses. Much …

The membrane-associated RING-CH (MARCH) proteins belong to a family of E3 ubiquitin
ligases, whose main function is to remove transmembrane proteins from the plasma …

The ser ine inc orporator (SERINC) proteins are multipass transmembrane proteins that
affect sphingolipid and phosphatidylserine synthesis. Human SERINC5 and SERINC3 were …

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (APOBEC3) proteins
(APOBEC3s) are deaminases that convert cytosines to uracils predominantly on a single …

Apolipoprotein B mRNA editing enzyme, catalytic peptide 3 (APOBEC3) proteins are critical
host proteins that counteract and prevent the replication of retroviruses. Unlike the genome …