The role of vascular cells during inflammation is critical and is of particular importance in
inflammatory diseases, including atherosclerosis, ischemia/reperfusion, and septic shock …

The liver directly accepts blood from the gut and is, therefore, exposed to intestinal bacteria.
Recent studies have demonstrated a relationship between gut bacteria and nonalcoholic …

From the mid‐1950s, it was observed that liver injury by a variety of toxins greatly sensitized
the host to the effects of administered lipopolysaccharide. In the nutritional cirrhosis of …

The role of the anti‐inflammatory cytokine interleukin‐10 (IL‐10) was investigated in the
mouse model of liver injury induced by carbon tetrachloride (CCl4). To address the role of …

The liver protects the host from gut-derived pathogens yet is tolerant of antigenic challenge
from food and commensal sources. Innate responses involving liver macrophages (Kupffer …

Inflammatory stimuli and lipid peroxidation activate nuclear factor kappa B (NF-κB) and
upregulate proinflammatory cytokines and chemokines. The present study evaluated the …

There are five nuclear factor‐κB (NF‐κB) transcription factors with important roles in innate
immunity, liver inflammation, fibrosis and apoptosis prevention. Several inhibitors of NF‐κB …

Ischemia/reperfusion injury of the liver requires the participation of proinflammatory
cytokines, chemokines, and adhesion molecules, many of which are regulated by the …

BACKGROUND/AIMS: Interleukin-10 (IL-10), exerts a protective role in hepatic damage
caused by viruses, alcohol, autoimmunity and a number of experimental aggressors …

There are several hypotheses that explain the process of acute inflammation, including free
radical overproduction, pro-inflammatory enzyme activation, and release of pro-inflammatory …